G
Glen A. Doherty
Researcher at University College Dublin
Publications - 172
Citations - 5780
Glen A. Doherty is an academic researcher from University College Dublin. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 32, co-authored 157 publications receiving 4525 citations. Previous affiliations of Glen A. Doherty include Harvard University & Mater Misericordiae University Hospital.
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Journal ArticleDOI
European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease.
Jean-François Rahier,Fernando Magro,Candida Abreu,Alessandro Armuzzi,Shomron Ben-Horin,Yehuda Chowers,Mario Cottone,L. de Ridder,Glen A. Doherty,Robert Ehehalt,Maria Esteve,K.H. Katsanos,Charlie W. Lees,Eithne MacMahon,Tom G. Moreels,Walter Reinisch,Herbert Tilg,Lydjie Tremblay,Gigi Veereman-Wauters,N. Viget,Yazdan Yazdanpanah,Rami Eliakim,Jean-Frederic Colombel +22 more
TL;DR: The treatment of inflammatory bowel disease has been revolutionised over the past decade by the increasing use of immunomodulators, mainly azathioprine/6-mercaptopurine and methotrexate, together with the advent of biological therapy.
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ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment
Joana Torres,Stefanos Bonovas,Glen A. Doherty,Torsten Kucharzik,Javier P. Gisbert,Tim Raine,Michel Adamina,Michel Adamina,Alessandro Armuzzi,Oliver Bachmann,Palle Bager,Livia Biancone,Bernd Bokemeyer,Peter Bossuyt,Johan Burisch,Paul Collins,Alaa El-Hussuna,Pierre Ellul,Cornelia Frei-Lanter,Federica Furfaro,Christian Gingert,Paolo Gionchetti,Fernando Gomollón,Marien González-Lorenzo,Hannah Gordon,Tibor Hlavaty,Pascal Juillerat,Konstantinos H. Katsanos,Uri Kopylov,Eduards Krustins,Theodore Lytras,Christian Maaser,Fernando Magro,John Marshall,Pär Myrelid,Gianluca Pellino,Isadora Rosa,João Sabino,Edoardo Savarino,Antonino Spinelli,Laurents P. S. Stassen,Mathieu Uzzan,Stephan R. Vavricka,Bram Verstockt,Janindra Warusavitarne,Oded Zmora,Gionata Fiorino +46 more
TL;DR: The present article addresses surgical management, including preoperative aspects and drug management before surgery, and provides technical advice for a variety of common clinical situations.
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An accelerated infliximab induction regimen reduces the need for early colectomy in patients with acute severe ulcerative colitis.
David J. Gibson,Zaid Heetun,Ciaran E. Redmond,Kavin S. Nanda,Denise Keegan,K. Byrne,Hugh Mulcahy,Garret Cullen,Glen A. Doherty +8 more
TL;DR: In patients with ASUC, an accelerated infliximab induction strategy reduces the need for early colectomy and an intensified inflIXimab dosing strategy in response to clinical or laboratory signs of breakthrough inflammation merits consideration in prospective studies.
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Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers
Aonghus Lavelle,Grainne Lennon,Orla O'Sullivan,Neil G. Docherty,Aine Balfe,Aoife Maguire,Hugh Mulcahy,Glen A. Doherty,D. P. O’Donoghue,John Hyland,R.P. Ross,John Calvin Coffey,Kieran Sheahan,Paul D. Cotter,Fergus Shanahan,Desmond C. Winter,P. R. O'Connell +16 more
TL;DR: This study demonstrates a conserved spatial structure to the colonic microbiota, differentiating the luminal and mucosal communities, within the context of marked interpersonal variability.
Journal ArticleDOI
Interventions for prevention of post‐operative recurrence of Crohn's disease
TL;DR: Nitro-imidazole antibiotics, mesalamine and immunosuppressive therapy with azathioprine/6-MP or infliximab all appear to be superior to placebo for the prevention of post-operative recurrence of Crohn's disease.