G
Glen P. Westall
Researcher at Alfred Hospital
Publications - 205
Citations - 4817
Glen P. Westall is an academic researcher from Alfred Hospital. The author has contributed to research in topics: Lung transplantation & Transplantation. The author has an hindex of 33, co-authored 181 publications receiving 3648 citations. Previous affiliations of Glen P. Westall include Monash University & Monash University, Clayton campus.
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Journal ArticleDOI
Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation
Deborah Levine,Allan R. Glanville,C.L Aboyoun,John A. Belperio,Christian Benden,Gerald J. Berry,Ramsey R. Hachem,Don Hayes,Desley Neil,Nancy L. Reinsmoen,Laurie D. Snyder,Stuart C. Sweet,Dolly B. Tyan,Geert Verleden,Glen P. Westall,Roger D. Yusen,Martin R. Zamora,Adriana Zeevi +17 more
TL;DR: A working group was created by the International Society for Heart and Lung Transplantation with the aim of determining criteria for pulmonary AMR and establishing a definition, and diagnostic criteria and a working consensus definition were established.
Journal ArticleDOI
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.
Marios Koutsakos,Adam K. Wheatley,Liyen Loh,E. Bridie Clemens,Sneha Sant,Simone Nüssing,Annette Fox,Amy W. Chung,Karen L. Laurie,Aeron C. Hurt,Steve Rockman,Martha Lappas,Thomas Loudovaris,Stuart I. Mannering,Glen P. Westall,Michael Elliot,Michael Elliot,Stuart G. Tangye,Stuart G. Tangye,Linda M. Wakim,Stephen J. Kent,Stephen J. Kent,Thi H. O. Nguyen,Katherine Kedzierska +23 more
TL;DR: It is suggested that a rational design of universal vaccines needs to consider circulating TFH cells, preexisting serological memory, and tissue compartmentalization for effective B cell immunity, as well as to improve targeting cellular T cell immunity.
Journal ArticleDOI
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses
Marios Koutsakos,Patricia T. Illing,Thi H. O. Nguyen,Nicole A. Mifsud,Jeremy Chase Crawford,Simone Rizzetto,Auda A. Eltahla,E. Bridie Clemens,Sneha Sant,Brendon Y. Chua,Brendon Y. Chua,Chinn Yi Wong,E. Kaitlynn Allen,Don Teng,Pradyot Dash,David F. Boyd,Ludivine Grzelak,Ludivine Grzelak,Weiguang Zeng,Aeron C. Hurt,Aeron C. Hurt,Ian G. Barr,Ian G. Barr,Ian G. Barr,Steve Rockman,David C. Jackson,David C. Jackson,Tom Kotsimbos,Tom Kotsimbos,Allen C. Cheng,Michael J Richards,Glen P. Westall,Thomas Loudovaris,Stuart I. Mannering,Michael Elliott,Michael Elliott,Stuart G. Tangye,Stuart G. Tangye,Linda M. Wakim,Jamie Rossjohn,Jamie Rossjohn,Jamie Rossjohn,Dhanasekaran Vijaykrishna,Fabio Luciani,Paul G. Thomas,Stephanie Gras,Stephanie Gras,Anthony W. Purcell,Katherine Kedzierska +48 more
TL;DR: This study introduces a new paradigm whereby CD8+ T cells confer unprecedented cross-reactivity across all influenza viruses, a key finding for the design of universal vaccines.
Journal ArticleDOI
MAIT cells protect against pulmonary Legionella longbeachae infection.
Huimeng Wang,Criselle D'Souza,Xin Yi Lim,Lyudmila Kostenko,Troi J. Pediongco,Sidonia B G Eckle,Bronwyn S. Meehan,Mai Shi,Nancy Wang,Shihan Li,Shihan Li,Ligong Liu,Jeffrey Y. W. Mak,David P. Fairlie,Yoichiro Iwakura,Jennifer M. Gunnersen,Andrew Stent,Dale I. Godfrey,Dale I. Godfrey,Jamie Rossjohn,Jamie Rossjohn,Jamie Rossjohn,Glen P. Westall,Lars Kjer-Nielsen,Richard A. Strugnell,James McCluskey,Alexandra J. Corbett,Timothy S. C. Hinks,Timothy S. C. Hinks,Zhenjun Chen +29 more
TL;DR: It is shown that mouse Legionellalongbeachae infection induces MR1-dependent MAIT cell activation and rapid pulmonary accumulation of MAIT cells associated with immune protection detectable in immunocompetent host animals, which indicates a potential role for vaccination to enhanceMAIT cell immunity.
Journal ArticleDOI
Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles
Angela Pizzolla,Thi H. O. Nguyen,Sneha Sant,Jade Jaffar,Thomas Loudovaris,Stuart I. Mannering,Paul G. Thomas,Glen P. Westall,Glen P. Westall,Katherine Kedzierska,Linda M. Wakim +10 more
TL;DR: The data reveal diverse TCR profiles within the human lung Trm cells and a high degree of clonal sharing with other CD8+ T cell populations, a feature important for effective T cell function and protection against the generation of viral-escape mutants.