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Gonçalo R. Abecasis

Researcher at University of Michigan

Publications -  629
Citations -  271012

Gonçalo R. Abecasis is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 179, co-authored 595 publications receiving 230323 citations. Previous affiliations of Gonçalo R. Abecasis include Johns Hopkins University School of Medicine & Wellcome Trust Centre for Human Genetics.

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Journal ArticleDOI

Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project

Mengyuan Kan, +42 more
- 13 Jan 2016 - 
TL;DR: This study indicates that the combined effect of rare variants contribute to the inter-individual variation in fat distribution through the regulation of insulin response.
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No bias in linkage analysis.

Gonçalo R. Abecasis, +7 more
- 01 Oct 2004 - 
TL;DR: The alarming claim that nonparametric linkage analysis methods have a previously unrecognized inherent bias against detection of linkage and proposed that linkage studies that have used these methods should be reexamined is not well founded.
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Correction to: Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools (PLoS Genet, (2015), 11(9))

Jun Ding, +14 more
- 29 Sep 2015 - 
TL;DR: This is the largest population analysis to date of mtDNA dynamics, revealing the age-imposed increase in heteroplasmy, the relatively high heritability of copy number, and the association ofcopy number with metabolic traits.
Posted ContentDOI

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

Natasha H. J. Ng, +323 more
- 03 Oct 2019 - 
TL;DR: In this paper, the authors investigated associations of exome-array variants in up to 144,060 individuals without diabetes of multiple ancestries, and found that a novel FG/FI association at the liver-enriched G6PC transcript was driven by multiple rare loss-of-function variants.
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Identification of CFTR variants in Latino patients with cystic fibrosis from the Dominican Republic and Puerto Rico.

Andrew M. Zeiger, +16 more
- 01 Feb 2020 - 
TL;DR: In cystic fibrosis (CF), the spectrum and frequency ofCFTR variants differ by geography and race/ethnicity, and CFTR variants in White patients are well‐described compared with Latino patients.