Gonzalo Rincon

TL;DR: To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage and provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.

TL;DR: This is the first study to describe the comprehensive bovine milk transcriptome in Holstein cows and reveals that 69% of NCBI Btau 4.0 annotated genes are expressed in bovin milk somatic cells, indicating the ability of milk somatics cells to adapt to different molecular functions according to the biological need of the animal.

TL;DR: The findings support the essentiality of milk to the survival of mammalian neonates and the establishment of milk secretory mechanisms more than 160 million years ago and suggest that this diversity of milk protein composition across species is primarily due to other mechanisms.

TL;DR: The results confirm that analyzing the transcriptome using RNA-Seq technology is an efficient and cost-effective method to identify SNPs in transcribed regions and provides more than 33,000 SNPs located in coding regions of genes expressed during lactation that can be used to develop genotyping platforms to perform marker-trait association studies in Holstein cattle.

TL;DR: The results indicate that the SC and MFG transcriptome are representative of MGT and LCMEC and can be used as effective and alternative samples to study mammary gland expression without the need to perform a tissue biopsy.