Author
Gorazd Sorsak
Bio: Gorazd Sorsak is an academic researcher from University of Ljubljana. The author has contributed to research in topics: Alkyl & Nucleophile. The author has an hindex of 6, co-authored 19 publications receiving 121 citations.
Topics: Alkyl, Nucleophile, Enol, Pyran, Hydrazine
Papers
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TL;DR: In this paper, a new reagent for the synthesis of hetero-cyclic β-amino-α,β-dehydro amino acid derivatives and some fused heterocyclic systems was obtained from N-2,2-bis(ethoxycarbonyl)vinyl glycinate and N-N-dimethyl-formamide dimethyl acetal.
29 citations
23 citations
TL;DR: In this paper, the 2.2-dibenzoylmethane was used as a reagent for preparation of fused substituted 3-aminopyranones and quinolizin-4-one.
20 citations
TL;DR: In this article, 5-(dimethylamino)methylidene substituted hydantoin and thiohydantoin derivatives with carbocyclic C-nucleophiles were determined by NMR, using NOESY and 2D HMBC techniques.
Abstract: 3-Substituted 5-[(Z)-heteroarylmethylidene]imidazolidine-2,4-dione and 5-[(Z)-heteroarylmethylidene]-2-thiooxoimidazolidin-4-one derivatives were prepared stereoselectively by coupling of 5-(dimethylamino)methylidene substituted hydantoin and thiohydantoin derivatives with carbocyclic and heterocyclic C-nucleophiles. Configuration around the exocyclic C=C double bond was determined by NMR, using NOESY and 2D HMBC techniques.
17 citations
TL;DR: In this article, a simple stereoselective synthesis of 2Z and 2Z, 1′E alkyl 3-acyloxy-2-(2,2-disubstituted ethenyl) aminopropenoates 4 from alkyyl 2-(2.2, 2, 2-dimethylaminopro-enoates) amino-3-dimethyl) was presented in 12-91% yield.
8 citations
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448 citations
430 citations
TL;DR: In this paper, the authors present a review of recent developments in the history of theYDANTOIN CHEMISTRY, focusing on the use of chemical compounds in the production of synthetic drugs.
197 citations
69 citations
57 citations