G
Gordon H. Guyatt
Researcher at McMaster University
Publications - 1749
Citations - 262329
Gordon H. Guyatt is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 231, co-authored 1620 publications receiving 228631 citations. Previous affiliations of Gordon H. Guyatt include Memorial Sloan Kettering Cancer Center & Cayetano Heredia University.
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Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study.
Marko Mrkobrada,Matthew T. V. Chan,David Cowan,Douglas M Campbell,Chew Yin Wang,David Torres,Germán Málaga,Robert D. Sanders,Manas Sharma,Carl J. Brown,Alben Sigamani,Wojciech Szczeklik,Mukul Sharma,Gordon H. Guyatt,Eric E. Smith,Ronit Agid,Adam A Dmytriw,Jessica Spence,Nikesh R. Adunuri,Flávia Kessler Borges,Timothy G. Short,Michael D. Hill,Feryal Saad,Ingrid Copland,Shirley Pettit,Quazi Ibrahim,Shrikant I. Bangdiwala,Salim Yusuf,Scott Tsai,Demetrios J. Sahlas,Arun Mensinkai,Luciano A. Sposato,Sara Hussain,Steven Yang,Deborah M. Siegal,Alexander Khaw,Jennifer Mandzia,Sara Simpson,Manoj J. Raval,Ahmer A. Karimuddin,PT Phang,Vincent Mok,William K.K. Wu,Simon Ch Yu,Tony Gin,Pui San Loh,Mun Thing Liew,Norlisah Ramli,Yee Lein Siow,Maite Fuentes,Victor Ortiz-Soriano,Ellen Waymouth,Jonathan Kumar,Divya Sadana,Lenimol Thomas,Bogusz Kaczmarek,Heidi Lindroth,Daniel I. Sessler,Sarah Apolcer,Amelia Trombetta,Stephanie Handsor,Monidipa Dasgupta,John M. Murkin,Shun Fu Lee,Philip J. Devereaux +64 more
TL;DR: NeuroVISION assessed patients aged 65 years or older who underwent inpatient, elective, non-cardiac surgery and had brain MRI after surgery to investigate the relationship between perioperative covert stroke and cognitive decline 1 year after surgery and the association with an increased risk of cognitive decline.
Journal ArticleDOI
GRADE guidelines: 21 part 2. Inconsistency, Imprecision, publication bias and other domains for rating the certainty of evidence for test accuracy and presenting it in evidence profiles and summary of findings tables.
Holger J. Schünemann,Reem A. Mustafa,Jan Brozek,Karen R Steingart,Mariska M.G. Leeflang,Mohammad Hassan Murad,Patrick M.M. Bossuyt,Paul Glasziou,Roman Jaeschke,Stefan Lange,Joerg J Meerpohl,Miranda W. Langendam,Monica Hultcrantz,Gunn Elisabeth Vist,Elie A. Akl,Mark Helfand,Nancy Santesso,Lotty Hooft,Rob J. P. M. Scholten,Måns Rosén,Anne W S Rutjes,Mark Crowther,Paola Muti,Heike Raatz,Mohammed T. Ansari,John W Williams,Regina Kunz,Jeffrey R. Harris,Ingrid Arévalo Rodriguez,Mikashmi Kohli,Gordon H. Guyatt +30 more
TL;DR: In this paper, the authors of systematic reviews and health technology assessment (HTA) and guideline developers can rate the certainty of evidence (also known as quality of the evidence or confidence in the estimates) of a body of evidence addressing test accuracy (TA) on the domains imprecision, inconsistency, publication bias and other domains.
Journal ArticleDOI
N of 1 randomized trials for investigating new drugs.
Gordon H. Guyatt,Arend Heyting,Roman Jaeschke,Jana L. Keller,Jonathan D. Adachi,Robin S. Roberts +5 more
TL;DR: N of 1 RCTs can be used to define the rapidity with which a drug begins and ceases its clinical action, the likely range of the optimal drug dose, and the optimal outcomes on which subsequent trials should focus.
Combined Corticosteroid and Antiviral Treatment for Bell Palsy
R. de Almeida,Gordon H. Guyatt,Ian J. Witterick,Vincent Y. W. Lin,Julian M. Nedzelski,Joseph M. Chen +5 more
TL;DR: In this paper, the association of corticosteroids and antiviral agents with the risk of unsatisfactory facial recovery in patients with Bell palsy was investigated using randomized controlled trials.
Journal ArticleDOI
In the dark: the reporting of blinding status in randomized controlled trials.
Victor M. Montori,Mohit Bhandari,Philip J. Devereaux,Braden J. Manns,William A. Ghali,Gordon H. Guyatt +5 more
TL;DR: In conclusion, prestigious journals should abandon the term "double blind" and explicitly report the blinding status of the groups involved in RCTs, and clinicians will be left with uncertainty about the validity of R CTs that guide their clinical practice.