G
Gourav Choudhir
Researcher at Indian Institute of Technology Delhi
Publications - 12
Citations - 249
Gourav Choudhir is an academic researcher from Indian Institute of Technology Delhi. The author has contributed to research in topics: Medicine & Docking (animal). The author has an hindex of 4, co-authored 7 publications receiving 124 citations. Previous affiliations of Gourav Choudhir include Chaudhary Charan Singh University.
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Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches.
Anuj Kumar,Gourav Choudhir,Sanjeev Kumar Shukla,Mansi Sharma,Pankaj Tyagi,Arvind Bhushan,Madhu Rathore +6 more
TL;DR: Novel natural metabolites namely, ursolic acid, carvacrol and oleanolic acid are reported as the potential inhibitors against main protease (Mpro) of COVID-19 by using integrated molecular modeling approaches.
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In silico studies evidenced the role of structurally diverse plant secondary metabolites in reducing SARS-CoV-2 pathogenesis.
Hariprasad Puttaswamy,Hittanahallikoppal Gajendramurthy Gowtham,Monu Dinesh Ojha,Ajay Yadav,Gourav Choudhir,Vasantharaja Raguraman,Bhani Kongkham,Koushalya Selvaraju,Shazia Shareef,Priyanka Gehlot,Faiz Ahamed,Leena Chauhan +11 more
TL;DR: The present study provides a platform for researchers to explore the possible use of selected PSM to prevent/ cure the COVID-19 by subjecting them for thorough in vitro and in vivo evaluation for the capabilities to interfering with the process of viral host cell recognition, entry and replication.
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Finding potent inhibitors for COVID-19 main protease (M pro ): an in silico approach using SARS-CoV-3CL protease inhibitors for combating CORONA.
Mohit Motiwale,Neetu Yadav,Sushil Kumar,Tushar Kushwaha,Gourav Choudhir,Supriya Sharma,Pradeep Kumar Singour +6 more
TL;DR: N-substituted isatin derivatives and pyrazolone compounds could be used as a potent inhibitor and may possess an anti-viral activity against SARS-CoV-2, however, further experimental investigation and validation of the selected hits are required to find out their suitability for clinical trials.
Posted ContentDOI
Natural compounds as potential inhibitors of novel coronavirus (COVID-19) main protease: An in silico study
Amaresh Chandra Mishra,Yamini Pathak,Gourav Choudhir,Anuj Kumar,Surabhi Kirti Mishra,Vishwas Tripathi +5 more
TL;DR: Amaresh Mishra Gautam Buddha University, Greater Noida, India Yamini Pathak GautAM Buddha University; Surabhi Kirti Mishra School of Biotechnology, Jawaharlal Nehru University, New Delhi, India.
Journal ArticleDOI
Molecular docking and dynamics studies of curcumin with COVID-19 proteins
Renuka Suravajhala,Abhinav Parashar,Gourav Choudhir,Anuj Kumar,Babita Malik,Viswanathan Arun Nagaraj,Govindarajan Padmanaban,Rathnagiri Polavarapu,Prashanth Suravajhala,P. B. Kavi Kishor +9 more
TL;DR: In this paper, the binding potential of curcumin targeted to a variety of SARS-CoV-2 proteins, viz. spike glycoproteins (PDB ID: 6VYB), nucleocapsid phosphoprotein, spike protein-ACE2, along with nsp10 and RNA dependent RNA polymerase, was investigated.