Greg A. Johnson

TL;DR: HOTAIR expression is increased in pancreatic tumors compared with non-tumor tissue and is associated with more aggressive tumors, and HOTAIR uniquely suppressed several interferon-related genes and gene sets related to cell cycle progression in Pancic cancer cells and tumors.

TL;DR: That disruption of uterine development during critical organizational periods can alter the functional capacity and embryotrophic potential of the adult uterus reinforces the importance of understanding the developmental biology of uterusine glands.

TL;DR: There is compelling evidence that uterine receptivity to implantation involves temporal and cell-specific expression of interferon (IFN)-stimulated genes that have many roles including nutrient transport, cellular remodeling, angiogenesis and relaxation of vascular tissues, cell proliferation and migration, establishment of an antiviral state, and protection of conceptus tissues from challenges by the maternal immune cells.

TL;DR: The sequential, overlapping actions of progesterone, IFNτ, placental lactogen (PL), and growth hormone (GH) comprise a hormonal servomechanism that regulates endometrial gland morphogenesis and terminal differentiated function during gestation.

TL;DR: Subsequently, sequential, overlapping actions of progesterone, interferon tau, placental lactogen, and growth hormone comprise a hormonal servomechanism that regulates endometrial gland morphogenesis and terminal differentiated function to maintain pregnancy in sheep.