G
Griffin P. Rodgers
Researcher at National Institutes of Health
Publications - 182
Citations - 8794
Griffin P. Rodgers is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Sickle cell anemia & Fetal hemoglobin. The author has an hindex of 45, co-authored 175 publications receiving 8011 citations. Previous affiliations of Griffin P. Rodgers include Nippon Medical School & University of the West Indies.
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Journal ArticleDOI
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
Mark T. Gladwin,Vandana Sachdev,Maria Jison,Yukitaka Shizukuda,Jonathan F. Plehn,Karin R. Minter,Bernice Brown,Wynona Coles,James S. Nichols,Inez Ernst,Lori A. Hunter,William C. Blackwelder,Alan N. Schechter,Griffin P. Rodgers,Oswaldo Castro,Frederick P. Ognibene +15 more
TL;DR: Pulmonary hypertension appears to be a complication of chronic hemolysis, is resistant to hydroxyurea therapy, and confers a high risk of death in adults with sickle cell disease.
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Allogeneic Hematopoietic Stem-Cell Transplantation for Sickle Cell Disease
Matthew M. Hsieh,Elizabeth M. Kang,Courtney D. Fitzhugh,M. Beth Link,Charles D. Bolan,Roger Kurlander,Richard W. Childs,Griffin P. Rodgers,Jonathan D. Powell,John F. Tisdale +9 more
TL;DR: A protocol for nonmyeloablative allogeneic hematopoietic stem-cell transplantation that includes total-body irradiation and treatment with alemtuzumab and sirolimus can achieve stable, mixed donor-recipient chimerism and reverse the sickle cell phenotype.
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Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences
TL;DR: Neutrophils normally comprise most circulating leukocytes and are critical in providing antimicrobial activity against bacteria and fungi, which implies that isolated minor reductions in peripheral neutrophils should not lead to increased risk for opportunistic infection.
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Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea.
Griffin P. Rodgers,George J. Dover,Constance Tom Noguchi,Alan N. Schechter,Arthur W. Nienhuis +4 more
TL;DR: It is concluded that hydroxyurea is effective in increasing the production of fetal hemoglobin, which in this study was found to be associated with a small decrease in hemolysis and an increase in hemoglobin levels despite myelosuppression.