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Guido Bondolfi

Researcher at University of Geneva

Publications -  146
Citations -  6128

Guido Bondolfi is an academic researcher from University of Geneva. The author has contributed to research in topics: Medicine & Mindfulness. The author has an hindex of 33, co-authored 128 publications receiving 5340 citations. Previous affiliations of Guido Bondolfi include Geneva College & GlaxoSmithKline.

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Decreased serum brain-derived neurotrophic factor levels in major depressed patients.

TL;DR: It is suggested that major depression is characterized by low serum BDNF levels and support the hypothesis of neurotrophic factor involvement in affective disorders.
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Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity.

TL;DR: The results suggest that an alteration of serum or plasma BDNF is probably related to mechanisms of BDNF release and seems to be independent of platelet reactivity; other mechanisms are therefore probably involved and need to be elucidated.
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Risperidone Versus Clozapine in Treatment-Resistant Chronic Schizophrenia: A Randomized Double-Blind Study

TL;DR: Risperidone was well tolerated and as effective as medium doses of clozapine in patients with chronic schizophrenia who had been resistant to or intolerant of conventional neuroleptics.
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Partial Normalization of Serum Brain-Derived Neurotrophic Factor in Remitted Patients after a Major Depressive Episode

TL;DR: It is suggested that antidepressant treatment has a positive effect on serum BDNF levels and support the hypothesis of neurotrophic factor involvement in affective disorders.