G
Guido Kroemer
Researcher at Institut Gustave Roussy
Publications - 1546
Citations - 294816
Guido Kroemer is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 236, co-authored 1404 publications receiving 246571 citations. Previous affiliations of Guido Kroemer include Karolinska Institutet & Spanish National Research Council.
Papers
More filters
Journal ArticleDOI
Functions of BCL-XL at the Interface between Cell Death and Metabolism
Judith Michels,Oliver Kepp,Laura Senovilla,Delphine Lissa,Maria Castedo,Guido Kroemer,Lorenzo Galluzzi +6 more
TL;DR: The functions of BCL-XL at the interface between cell death and metabolism are discussed, which appear to play a prominent role in the regulation of multiple distinct types of cell death, including apoptosis and regulated necrosis.
Journal ArticleDOI
The dendritic cell-tumor cross-talk in cancer.
Yuting Ma,Laetitia Aymeric,Laetitia Aymeric,Laetitia Aymeric,Clara Locher,Clara Locher,Clara Locher,Guido Kroemer,Laurence Zitvogel +8 more
TL;DR: The novel mechanisms by which tumor cells regulate DC recruitment, differentiation, activation and cross-presenting functions in tumor beds and how innate players might counterbalance these interactions are summarized.
Journal ArticleDOI
How to improve the immunogenicity of chemotherapy and radiotherapy
Yuting Ma,Yuting Ma,Yuting Ma,Rosa Conforti,Rosa Conforti,Rosa Conforti,Laetitia Aymeric,Laetitia Aymeric,Laetitia Aymeric,Clara Locher,Clara Locher,Clara Locher,Oliver Kepp,Oliver Kepp,Guido Kroemer,Laurence Zitvogel +15 more
TL;DR: This work summarized some of the cell death-derived danger signals and the mechanism for host to sense and response to cell death in the tumor microenvironment and suggested strategies to improve the immunogenicity of cell death and augment antitumor immunity.
Journal ArticleDOI
Molecular mechanisms of selective autophagy.
TL;DR: This thematic issue, five reviews summarize the mechanistic and structural basis of receptor-mediated selective autophagy, and discusses the current knowledge of the most prominent mammalian adaptor protein identified thus far, Autophagy-linked FYVE protein (ALFY).
Journal ArticleDOI
Mitochondrial Control of Cell Death Induced by HIV-1-Encoded Proteins
TL;DR: The data suggest the possibility that viruses employ multiple strategies to regulate host cell apoptosis by targeting mitochondria, and the structural motifs of the Vpr protein involved in MMP are conserved among most pathogenic HIV‐1 isolates.