Guifan Sun

TL;DR: A statistical risk model is developed that classifies safe and unsafe areas with respect to geogenic arsenic contamination in China, using the threshold of 10 micrograms per liter, the World Health Organization guideline and current Chinese standard for drinking water.

TL;DR: The results support the possibility of an adverse effect of high fluoride exposure on children’s neurodevelopment and recommend further research on prenatal exposure, neurobehavioral performance, and covariates for adjustment.

TL;DR: Evidence is provided that chronic exposure to arsenic from drinking water in humans results in induction of oxidative stress, as indicated by the reduction in NPSH and the increase in LPO.

TL;DR: From the research, it is found that new endemic areas of arsenicosis are continuously emerging in China, and the discovery of wells and coal with high levels of arsenic is continuing sporadically, and a similar scattered distribution pattern of patients is also being observed.

TL;DR: In an in vitro study, it is demonstrated that inorganic arsenite or arsenate suppresses the activity of endothelial NO synthase in human umbilical vein endothelial cells, suggesting that long-term exposure to arsenic by drinking well water possibly reduces NO production in endothelial Cells, resulting in a decrease in reduced nitrite/nitrate concentrations.