Guillemette Gauquelin-Koch

TL;DR: For the first time, a simple countermeasure is reported that prevents the deleterious adaptations of the major physiological functions affected by mechanical unloading, and resveratrol is envisaged as a nutritional counter‐measure for spaceflight.

TL;DR: The main sections of the paper discuss the changes induced by long-term dry immersion in the neuromuscular and sensorimotor systems, fluid–electrolyte regulation, the cardiovascular system, metabolism, blood and immunity, respiration, and thermoregulation.

TL;DR: The finding of sodium gain without weight gain is in contradiction to the widely accepted theory that changes in TBS levels are accompanied by changes in extracellular volume, and suggests the existence of a sodium reservoir with the ability to store significant amounts of sodium in an osmotically inactive form.

TL;DR: During prolonged HDBR no relevant modifications in water metabolism were triggered, and body weight alone does not accurately reflect the subject's energy state, and energy balance alone could not explain the body weight loss, which involves a transient metabolic stress.

TL;DR: While saturated and monounsaturated fats have similar plasma trafficking and clearance, physical inactivity affects the partitioning of saturated fats toward storage, likely leading to an accumulation of palmitate in muscle fat.