Author
Guleray Agar
Other affiliations: Agricultural University of Athens, Laboratory of Molecular Biology
Bio: Guleray Agar is an academic researcher from Atatürk University. The author has contributed to research in topics: RAPD & DNA damage. The author has an hindex of 22, co-authored 140 publications receiving 2582 citations. Previous affiliations of Guleray Agar include Agricultural University of Athens & Laboratory of Molecular Biology.
Topics: RAPD, DNA damage, DNA methylation, Essential oil, Gibberellic acid
Papers published on a yearly basis
Papers
More filters
••
TL;DR: In this article, the antimicrobial properties of essential oils and methanol extracts of Origanum vulgare ssp. were evaluated using a GC/MS system and the results showed that the essential oil of O. vulgaare possesses great potential of antimicrobial activity against all 10 bacteria and 15 fungi and yeast species tested.
475 citations
••
TL;DR: The antimicrobial and antioxidant activities of the essential oil, obtained by using a Clevenger distillation apparatus, water soluble and water insoluble subfraction of the methanol extracts from aerial parts of Satureja hortensis L.hortensis, showed great potential antimicrobial activities against all 23 bacteria and 15 fungi and yeast species tested.
Abstract: The present study was designated to evaluate the antimicrobial and antioxidant activities of the essential oil, obtained by using a Clevenger distillation apparatus, water soluble (polar) and water insoluble (nonpolar) subfractions of the methanol extracts from aerial parts of Satureja hortensis L plants, and methanol extract from calli established from the seeds using Gamborg's B5 basal media supplemented with indole-3-butyric acid (10 ppm), 6-benzylaminopurine (N(6)-benzyladenine) (10 ppm), and sucrose (25%) The antimicrobial test results showed that the essential oil of S hortensis had great potential antimicrobial activities against all 23 bacteria and 15 fungi and yeast species tested In contrast, the methanol extract from callus cultures and water soluble subfraction of the methanol extract did not show antimicrobial activities, but the nonpolar subfraction had antibacterial activity against only five out of 23 bacterial species, which were Bacillus subtilis, Enterococcus fecalis, Pseudomonas aeruginosa, Salmonella enteritidis, and Streptococcus pyogenes Antioxidant studies suggested that the polar subfractions of the methanol extract of intact plant and methanol extract of callus cultures were able to reduce the stable free radical 2,2-diphenyl-1-picrylhydrazyl to the yellow-colored diphenylpicrylhydrazine In this assay, the strongest effect was observed for the tissue culture extract, with an IC(50) value of 2376 +/- 080 microgram/mL, which could be compared with the synthetic antioxidant agent butylated hydroxytoluene On the other hand, linoleic acid oxidation was 95% inhibited in the presence of the essential oil while the inhibition was 90% with the chloroform subfraction of the intact plant The chemical composition of a hydrodistilled essential oil of S hortensis was analyzed by gas chromatography (GC)/flame ionization detection (FID) and a GC-mass spectrometry system A total 22 constituents representing 999% of the essential oil were identified by GC-FID analaysis Thymol (290%), carvacrol (265%), gamma-terpinene (226%), and p-cymene (93%) were the main components
416 citations
••
TL;DR: In this paper, methanol extracts of Parmelia saxatilis, Platismatia glauca, Ramalina pollinaria, R. polymorpha and U. nylanderiana were evaluated for antimicrobial and antioxidant activity.
174 citations
••
TL;DR: The results showed that Pb and Zn significantly delayed and impeded the germination of chickpea seeds and the negative effect of Pb on germination was higher than that of Zn.
Abstract: The present work describes the changes that take place in phytohormone contents in germinating chickpea (Cicer arietinum cv. Aziziye-94) seeds in response to heavy metal stress. For this aim, endogenous abscisic acid (ABA), gibberellic acid (GA3), zeatin (Z) and zeatin riboside (ZR) contents were followed for 24, 48 and 72 h in chickpea seeds germinating at the concentrations of 0.1, 1.0 and 5.0 mM Pb or 0.1, 1.0 and 10 mM Zn. The results showed that Pb and Zn significantly delayed and impeded the germination of chickpea seeds. The negative effect of Pb on germination was higher than that of Zn. Further, Pb increased ABA and Z contents while decreased GA3 content in the germinating seeds. The high concentrations of Zn (1.0 and 10 mM) decreased contents of Z, ZR and GA3 while 0.1 mM Zn increased the content of the same hormones. The ABA content was enhanced by Zn in all concentrations used.
172 citations
••
TL;DR: In conclusion, vitamin A, C, and E exhibited protective effects in human lymphocytes by inhibiting AFB1-induced ROS generation by inhibition of GSH and the activities of superoxide dismutase and GPx and increased level of malondialdehyde.
Abstract: The aim of this study was to investigate the possible protective role of vitamin A, C, and E on aflatoxin B(1)-induced in human lymphocytes using biochemical approaches. The control group received dimethyl sulfoxide, the second group of cultures were administered aflatoxin B(1) (AFB(1)) at a dose of 5 muM. The other group of cultures were treated with AFB(1)+vitamin A (0.5 and 1.0 and 1.5 microM) and AFB(1)+vitamin C (25, 50, and 100 microM) and AFB(1)+vitamin E (40, 100, and 200 microM). The results of this experiment show that AFB(1) significantly decreased the level of GSH and the activities of superoxide dismutase and GPx and increased level of malondialdehyde. Simultaneous supplementation with vitamin A, C, and E restored these parameters to that of normal range. In conclusion, vitamin A, C, and E exhibited protective effects in human lymphocytes by inhibiting AFB(1)-induced ROS generation.
107 citations
Cited by
More filters
•
01 Jan 1979
5,044 citations
••
1,390 citations
••
TL;DR: This review summarizes various tolerance strategies of plants under heavy metal toxicity covering the role of metabolites (metabolomics), trace elements (ionomics), transcription factors (transcriptomics), various stress-inducible proteins (proteomics) as well as therole of plant hormones.
Abstract: Heavy metal contamination of soil and water causing toxicity/stress has become one important constraint to crop productivity and quality. This situation has further worsened by the increasing population growth and inherent food demand. It have been reported in several studies that counterbalancing toxicity, due to heavy metal requires complex mechanisms at molecular, biochemical, physiological, cellular, tissue and whole plant level, which might manifest in terms of improved crop productivity. Recent advances in various disciplines of biological sciences such as metabolomics, transcriptomics, proteomics etc. have assisted in the characterization of metabolites, transcription factors, stress-inducible proteins involved in heavy metal tolerance, which in turn can be utilized for generating heavy metal tolerant crops. This review summarizes various tolerance strategies of plants under heavy metal toxicity, covering the role of metabolites (metabolomics), trace elements (ionomics), transcription factors (transcriptomics), various stress-inducible proteins (proteomics) as well as the role of plant hormones. We also provide a glance at strategies adopted by metal accumulating plants also known as “metallophytes”.
820 citations
••
TL;DR: Results showed that the most active essential oils against bacteria tested were Corydothymus capitatus, Cinnamomum cassia, Origanum heracleoticum, Satureja montana , and Cinnemomum verum (bark).
764 citations
••
TL;DR: The purpose of this review is to describe how plants take lead up and to link such uptake to the ecotoxicity of lead in plants, and to address the mechanisms by which plants or plant systems detoxify lead.
Abstract: Plants are the target of a wide range of pollutants that vary in concentration, speciation, and toxicity. Such pollutants mainly enter the plant system through the soil (Arshad et al. 2008) or via the atmosphere (Uzu et al. 2010). Among common pollutants that affect plants, lead is among the most toxic and frequently encountered (Cecchi et al. 2008; Grover et al. 2010; Shahid et al. 2011). Lead continues to be used widely in many industrial processes and occurs as a contaminant in all environmental compartments (soils, water, the atmosphere, and living organisms). The prominence of environmental lead contamination results both from its persistence (Islam et al. 2008; Andra et al. 2009; Punamiya et al. 2010) and from its present and past numerous sources. These sources have included smelting, combustion of leaded gasoline, or applications of lead-contaminated media (sewage sludge and fertilizers) to land (Piotrowska et al. 2009; Gupta et al. 2009; Sammut et al. 2010; Grover et al. 2010). In 2009, production of recoverable lead from mining operations was 1690, 516, and 400 thousand metric tons by China, Australia, and the USA, respectively (USGS 2009).
696 citations