Günther Sawitzki

TL;DR: Details of the aims and methods of Bioconductor, the collaborative creation of extensible software for computational biology and bioinformatics, and current challenges are described.

TL;DR: In this article, a method for analyzing the modality of a distribution is proposed based on the excess mass functional, which measures excessive empirical mass in comparison with multiples of uniform distribution.

TL;DR: The results give raise to the discussion if affective instability is a transdiagnostic or a disorder-specific mechanism, and investigating psychopathological mechanisms in everyday life across disorders is a promising approach to enhance validity and specificity of mental health diagnoses.

TL;DR: In this article, the authors used 24-hour ambulatory monitoring to assess subjective ratings of distress in 50 borderline personality disorder (BPD) patients and in 50 healthy controls and found that the chosen time-based design with a time interval of 15 min between self-reports (1) reveals within subject variability in BPD-patients and (2) taps the process of interest.

TL;DR: The results show considerable problems even in basic features of well-known systems, and the omissions and failures observed here give some suspicions of what happens in less well-understood problem areas of computational statistics.