G
Guosheng Mo
Researcher at South China University of Technology
Publications - 3
Citations - 21
Guosheng Mo is an academic researcher from South China University of Technology. The author has contributed to research in topics: Medicine & Trans-activating crRNA. The author has co-authored 2 publications.
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Rapid and accurate detection of SARS-CoV-2 mutations using a Cas12a-based sensing platform
He Changsheng,Cailing Lin,Guosheng Mo,Binbin Xi,An′an Li,Dongchao Huang,Yanbin Wan,Feng Chen,Yufeng Liang,Qingxia Zuo,Wanqing Xu,Dongyan Feng,Guanting Zhang,Liya Han,Changwen Ke,Hongli Du,Lizhen Huang +16 more
TL;DR: In this paper, a Cas12a-based RT-PCR combined with CRISPR on-site rapid detection system (RT-CORDS) platform was used to detect the key mutations in SARS-CoV-2 variants, such as 69/70 deletion, N501Y, and D614G.
Posted Content
Rapid and Accurate Detection of SARS-CoV-2 Mutations using a Cas12a-based Sensing Platform
He Changsheng,Cailing Lin,Guosheng Mo,Binbin Xi,An′an Li,Dongchao Huang,Yanbin Wan,Feng Chen,Yufeng Liang,Qingxia Zuo,Wanqing Xu,Dongyan Feng,Guanting Zhang,Liya Han,Changwen Ke,Hongli Du,Lizhen Huang +16 more
TL;DR: In this article, a Cas12a-based RT-PCR combined with CRISPR on-site rapid detection system (RT-CORDS) platform was used to detect the key mutations in SARS-CoV-2 variants, such as 69/70 deletion, N501Y, and D614G.
Journal ArticleDOI
Validation Study to Determine the Accuracy of Widespread Promoterless EGFP Reporter at Assessing CRISPR/Cas9-Mediated Homology Directed Repair
Wan Xu,Qingxia Zuo,Dongyan Feng,Changsheng He,Cailing Lin,Dongchao Huang,Yan Jin Wan,Feng Chen,Guosheng Mo,Qi Sun,Hongli Du,Lizhen Huang +11 more
TL;DR: The widespread promoterless EGFP reporter could not be an ideal measurement for HDR screening and there is an urgent need to develop a more reliable, high-resolution HDR screening system to better explore strategies of increasing the efficiency of Cas9-mediated HDR in mammalian cells.