Gustaaf J. Lankhorst

TL;DR: The Charlson Index, the CIRS, the ICED and the Kaplan Index are valid and reliable methods to measure comorbidity that can be used in clinical research.

TL;DR: Greater intensity of leg rehabilitation improves functional recovery and health-related functional status, whereas greater intensity of arm rehabilitation results in small improvements in dexterity, providing further evidence that exercise therapy primarily induces treatment effects on the abilities at which training is specifically aimed.

TL;DR: A small but lasting effect of forced use therapy on the dexterity of the affected arm (ARA) and a temporary clinically relevant effect on the amount of use of theaffected arm during activities of daily living (MAL amount ofUse) are shown.

TL;DR: The responsiveness to change of a health status measurement instrument is closely related to its test-retest reproducibility, and this relationship becomes more evident when the SEM and the SRD are used to quantify reproducible, than when ICC or other correlation coefficients are used.

TL;DR: A small but statistically significant intensity-effect relationship in the rehabilitation of stroke patients was found and insufficient contrast in the amount of rehabilitation between experimental and control conditions, organizational setting of rehabilitation management, lack of blinding procedures, and heterogeneity of patient characteristics were major confounding factors.