G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
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Journal ArticleDOI
Family-based association study of common variants, rare mutation study and epistatic interaction detection in HDAC genes in schizophrenia
Oussama Kebir,Oussama Kebir,Boris Chaumette,Boris Chaumette,Mar Fatjó-Vilas,Mar Fatjó-Vilas,Amirthagowri Ambalavanan,Nicolas Ramoz,Lan Xiong,Fayçal Mouaffak,Bruno Millet,Nematollah Jaafari,Lynn E. DeLisi,Douglas F. Levinson,Ridha Joober,Lourdes Fañanás,Lourdes Fañanás,Guy A. Rouleau,Guy A. Rouleau,Caroline Dubertret,Marie-Odile Krebs,Marie-Odile Krebs +21 more
TL;DR: This first exploratory systematic study of theHDAC genes provides consistent support for the involvement of the HDAC3 gene in the etiology of schizophrenia and a statistical epistatic interaction between HDAC9, HDAC10, and HDAC11 seems biologically plausible.
Journal ArticleDOI
Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17.
B. R. Seizinger,Guy A. Rouleau,A.H. Lane,G. E. Farmer,Laurie J. Ozelius,Jonathan Haines,Dilys M. Parry,Bruce R. Korf,Margaret A. Pericak-Vance,Anne G. Faryniarz,Wendy Hobbs,J.A. Iannazzi,J.C. Roy,Anil Menon,J.L. Bader,M.A. Spence,Moses V. Chao,John J. Mulvihill,A. D. Roses,Robert L. Martuza,Xandra O. Breakefield,P. M. Conneally,James F. Gusella +22 more
TL;DR: Linkage analysis with the human oncogene homolog erbA1, which maps to this region, suggests that this cancer-related gene is not the primary cause of NF1, and a preliminary multipoint linkage analysis suggests that the NF1 gene is located on the long arm of chroomsome 17.
Journal Article
Clonal analysis of human meningiomas and schwannomas.
TL;DR: It is concluded that human meningiomas and schwannomas arise from a single cell.
Journal ArticleDOI
MEIS1 and Restless Legs Syndrome: A Comprehensive Review.
TL;DR: The links to iron and the enhancer activity of the HCNRs of MEIS1 suggest promising links to RLS pathways, however more in-depth studies on this gene's function are required.
Journal ArticleDOI
Mutated GABAA receptor subunits in idiopathic generalized epilepsy
Patrick Cossette,Guy A. Rouleau +1 more
TL;DR: γ‐Aminobutyric acid (GABA)A receptors are ligand‐gated chloride channels that mediate fast synaptic inhibition in the brain that provide important insights into the pathogenesis of the disease.