G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
Papers
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Journal ArticleDOI
Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population
Sirui Zhou,Ziv Gan-Or,Ziv Gan-Or,Amirthagowri Ambalavanan,Amirthagowri Ambalavanan,Dongbing Lai,Pingxing Xie,Cynthia V. Bourassa,Stephanie Strong,Stephanie Strong,Jay P. Ross,Jay P. Ross,Alexandre Dionne-Laporte,Dan Spiegelman,Nicolas Dupré,Tatiana Foroud,Lan Xiong,Patrick A. Dion,Patrick A. Dion,Guy A. Rouleau,Guy A. Rouleau +20 more
TL;DR: Two new potential IA loci are identified in the French-Canadian population: FHIT, which is significantly associated with hypertensive IA, and CCDC80, which has potential genetic and functional relevance to IA pathogenesis, providing evidence on the additional risk loci for familial IA.
Journal ArticleDOI
Dinucleotide repeat polymorphism at the human CRYB2 gene locus(22q11.2)
Claude Marineau,Guy A. Rouleau +1 more
Journal ArticleDOI
Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder
Thomas W. Mühleisen,Céline S. Reinbold,Andreas J. Forstner,Lilia I. Abramova,Martin Alda,Gulja Babadjanova,Michael Bauer,Paul Brennan,Alexander Chuchalin,Cristiana Cruceanu,Piotr M. Czerski,Franziska Degenhardt,Sascha B. Fischer,Janice M. Fullerton,Scott D. Gordon,Maria Grigoroiu-Serbanescu,Paul Grof,Joanna Hauser,Martin Hautzinger,Stefan Herms,Per Hoffmann,Jutta Kammerer-Ciernioch,Elza Khusnutdinova,Manolis Kogevinas,Valery Krasnov,André Lacour,Catherine Laprise,Markus Leber,Jolanta Lissowska,Susanne Lucae,Anna Maaser,Wolfgang Maier,Nicholas G. Martin,Manuel Mattheisen,Fermín Mayoral,James McKay,Sarah E. Medland,Philip B. Mitchell,Susanne Moebus,Grant W. Montgomery,Bertram Müller-Myhsok,Lilijana Oruc,Galina Pantelejeva,Andrea Pfennig,Lejla Pojskic,Alexey Polonikov,Andreas Reif,Fabio Rivas,Guy A. Rouleau,Lorena M. Schenk,Peter R. Schofield,Markus Schwarz,Fabian Streit,Jana Strohmaier,Neonila Szeszenia-Dabrowska,Alexander S. Tiganov,Jens Treutlein,Gustavo Turecki,Helmut Vedder,Stephanie H. Witt,Thomas G. Schulze,Marcella Rietschel,Markus M. Nöthen,Sven Cichon +63 more
TL;DR: Pathway analysis in large GWAS data of BD and follow-up of gene expression patterns in healthy brains provide support for an involvement of neurodevelopmental processes in the etiology of this neuropsychiatric disease.
Journal ArticleDOI
Triple A syndrome presenting as complicated hereditary spastic paraplegia.
Etienne Leveille,Hernan Gonorazky,Marie-France Rioux,Lili-Naz Hazrati,Jennifer A. Ruskey,Jennifer A. Ruskey,Amanda Carnevale,Dan Spiegelman,Dan Spiegelman,Alexandre Dionne-Laporte,Alexandre Dionne-Laporte,Guy A. Rouleau,Guy A. Rouleau,Grace Yoon,Ziv Gan-Or,Ziv Gan-Or +15 more
TL;DR: Hereditary spastic paraplegia is a group of rare disorders characterized by spastics paraparesis and other symptoms and often other diseases can mimic HSP, which may delay diagnosis and treatment.
Journal ArticleDOI
Prospective head-to-head comparison of accuracy of two sequencing platforms for screening for fetal aneuploidy by cell-free DNA: the PEGASUS study.
François Rousseau,Sylvie Langlois,Jo-Ann Johnson,Jean Gekas,Emmanuel Bujold,François Audibert,Mark Walker,Mark Walker,Sylvie Giroux,André Caron,Valérie Clément,Jonatan Blais,Tina MacLeod,Richard A. Moore,Julie Gauthier,Loubna Jouan,Alexandre D. Laporte,Ousmane Diallo,Jeremy Parker,Lucas Swanson,Yongjun Zhao,Yves Labelle,Yves Giguère,Jean-Claude Forest,Julian Little,Aly Karsan,Guy A. Rouleau +26 more
TL;DR: Threshold analysis in high-risk pregnancies with different fetal fractions and z-score cut-offs suggested that a z- score cutoff to 3.5 for positive results improved test accuracy.