G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
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Proceedings ArticleDOI
Vision-Based Tracking and Trajectory Generation for Robotic Capture of Objects in Space
TL;DR: The development of vision-based algorithms for determining the motion of a moving object and generating trajectory for a robotic manipulator to intercept the object is described and simulation results demonstrating the performance of these algorithms are presented.
Journal ArticleDOI
Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease.
Fulya Akçimen,Fulya Akçimen,Sandra Martins,Sandra Martins,Calwing Liao,Calwing Liao,Cynthia V. Bourassa,Cynthia V. Bourassa,Hélène Catoire,Hélène Catoire,Garth A. Nicholson,Olaf Riess,Mafalda Raposo,Marcondes C. França,João Vasconcelos,Manuela Lima,Iscia Lopes-Cendes,Maria Luiza Saraiva-Pereira,Maria Luiza Saraiva-Pereira,Laura Bannach Jardim,Laura Bannach Jardim,Jorge Sequeiros,Jorge Sequeiros,Patrick A. Dion,Patrick A. Dion,Guy A. Rouleau,Guy A. Rouleau +26 more
TL;DR: This study demonstrates the existence of several additional genetic factors, along with CAG expansion, that may lead to a better understanding of the genotype-phenotype correlation in MJD.
A Comprehensive and Efficient Detection of Somatic Mutations by Denaturing HPLC and Microarray-CGH
Irene Szijan,Daniel Rochefort,Carl E.G. Bruder,Ezequiel Surace,Gloria A. Machiavelli,Viviana Dalamon,Javier Cotignola,Veronica Ferreiro,Alvaro Campero,Armando Basso,Jan P. Dumanski,Guy A. Rouleau +11 more
TL;DR: Results provide additional evidence that mutations in the NF2 gene play an important role in the development of sporadic meningiomas and schwannomas and complementary, fast, and efficient methods for the detection of mutations in tumor tissues.
Journal Article
Hereditary spastic paraplegia: LOD-score considerations for confirmation of linkage in a heterogeneous trait
Marie-Pierre Dubé,Melinda A. Mlodzienski,Zoha Kibar,Martin R. Farlow,George C. Ebers,Peter S. Harper,Edwin H. Kolodny,Guy A. Rouleau,Denise A. Figlewicz +8 more
TL;DR: A combined analytical approach permitted conclusive linkage analyses on small to medium-size families, under the restrictions of genetic heterogeneity, and established the critical LOD-score value necessary for confirmation of linkage to the SPG4 locus from Bayesian statistics.
Journal ArticleDOI
Intracranial Aneurysm Classifier Using Phenotypic Factors: An International Pooled Analysis
Sandrine Morel,Isabel C Hostettler,Georg Spinner,Romain Bourcier,Joanna Pera,Torstein R. Meling,Varinder S Alg,Henry Houlden,Mark K Bakker,F. van’t Hof,Gabriel J.E. Rinkel,Tatiana Foroud,Dongbing Lai,Charles J Moomaw,Bradford B. Worrall,Jildaz Caroff,Pacôme Constant-dits-Beaufils,Matilde Karakachoff,Antoine Rimbert,Aymeric Rouchaud,Emília Gaál-Paavola,H. Kaukovalta,Riku Kivisaari,Aki Laakso,Behnam Rezai Jahromi,Riikka Tulamo,Christoph M. Friedrich,Jérôme Dauvillier,Sven Hirsch,Nathalie Isidor,Zolt Kulcsár,Karl-Olof Lövblad,Olivier Martin,P. Machi,Vitor Mendes Pereira,Daniel A. Rüfenacht,Karl Lothard Schaller,Sabine Schilling,Agnieszka Slowik,J Jaaskelainen,M. von Und Zu Fraunberg,Jordi Jimenez-Conde,Elisa Cuadrado-Godia,Carolina Soriano-Tárraga,Iona Y. Millwood,Robin G. Walters,Helen Kim,Richard Redon,Nerissa U. Ko,Guy A. Rouleau,Antti E. Lindgren,Mika Niemelä,Hubert Desal,Daniel Woo,Joseph P. Broderick,David J. Werring,Ynte M. Ruigrok,Philippe Bijlenga +57 more
TL;DR: Assessment of associations regarding patient and IA characteristics with IA rupture allows us to refine IA disease models and provide data to develop risk instruments for clinicians to support personalized decision-making.