G
György Dormán
Researcher at Stony Brook University
Publications - 81
Citations - 3162
György Dormán is an academic researcher from Stony Brook University. The author has contributed to research in topics: Virtual screening & Inositol. The author has an hindex of 23, co-authored 77 publications receiving 2945 citations. Previous affiliations of György Dormán include University of Szeged & CytRx.
Papers
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Journal ArticleDOI
Benzophenone photophores in biochemistry
György Dormán,Glenn D. Prestwich +1 more
TL;DR: This Perspectives includes a brief review of BP photochemistry and a selection of specific applications of these photoprobes, which address questions in protein, nucleic acid, and lipid biochemistry.
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Using photolabile ligands in drug discovery and development.
György Dormán,Glenn D. Prestwich +1 more
TL;DR: Examples are presented from three fundamentally different approaches: (1) photoaffinity labeling of target macromolecules; (2) photoactivation and release of 'caged ligands'; and (3) photoimmobilization of ligands onto surfaces.
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Matrix metalloproteinase inhibitors: a critical appraisal of design principles and proposed therapeutic utility.
György Dormán,Sándor Cseh,István Hajdú,László Barna,Dénes Kónya,Krisztina Kupai,László Kovács,Péter Ferdinandy +7 more
TL;DR: This article critically review the major structural determinants of the selectivity and the milestones of past design efforts of MMPIs where 2-/3-dimensional structure-based methods were intensively applied, and analyse the in vitro screening and preclinical/clinical pharmacology approaches.
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The Life of Pi Star: Exploring the Exciting and Forbidden Worlds of the Benzophenone Photophore
TL;DR: The "forbidden" and excitation-activated world of photoinduced covalent attachment of BP photophores is explored by touring a colorful palette of recent examples, and it is hoped that both novice and expert photolabelers will be inspired by the breadth and depth of possibilities.
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Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor
Susan M. Voglmaier,Michael E. Bembenek,Adam I. Kaplin,György Dormán,John D. Olszewski,Glenn D. Prestwich,Solomon H. Snyder +6 more
TL;DR: This purified inositol hexakisphosphate kinase activity indicates the high phosphate group transfer potential of PP-IP5 and may represent a physiological role for PP- IP5.