H. M. C. Heick

Bio: H. M. C. Heick is an academic researcher. The author has contributed to research in topics: Ascorbic acid & Yeast. The author has an hindex of 2, co-authored 2 publications receiving 50 citations.

The occurrence of ascorbic acid among the yeasts.

Abstract: Forty-two species of yeast were examined for their ability to produce enediols of the ascorbic acid class. A Roe and Kuether chromogen derived from such enediols could be isolated from 23 of the species. The chromogen from four yeasts was further identified by infrared (i.r.) spectrophotometry as being derived from ascorbic acid. At least one species from each family of yeasts was found to produce ascorbic acid.

Occurrence of ascorbic acid in the yeast Lipomyces starkeyi

Abstract: Ascorbic acid was identified in cultures of the yeast Lipomyces starkeyi. The acid was identified by preparing the Roe and Kuether chromogen and comparing its infrared spectrum with the spectra of ...

Plant L‐ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

Abstract: Humans are unable to synthesise L-ascorbic acid (L-AA, ascorbate, vitamin C), and are thus entirely dependent upon dietary sources to meet needs. In both plant and animal metabolism, the biological functions of L-ascorbic acid are centred around the antioxidant properties of this molecule. Considerable evidence has been accruing in the last two decades of the importance of L-AA in protecting not only the plant from oxidative stress, but also mammals from various chronic diseases that have their origins in oxidative stress. Evidence suggests that the plasma levels of L-AA in large sections of the population are sub-optimal for the health protective effects of this vitamin. Until quite recently, little focus has been given to improving the L-AA content of plant foods, either in terms of the amounts present in commercial crop varieties, or in minimising losses prior to ingestion. Further, while L-AA biosynthesis in animals was elucidated in the 1960s, 1 it is only very recently that a distinct biosynthetic route for plants has been proposed. 2 The characterisation of this new pathway will undoubtedly provide the necessary focus and impetus to enable fundamental questions on plant L-AA metabolism to be resolved. This review focuses on the role of L-AA in metabolism and the latest studies regarding its bio- synthesis, tissue compartmentalisation, turnover and catabolism. These inter-relationships are considered in relation to the potential to improve the L-AA content of crops. Methodology for the reliable analysis of L-AA in plant foods is briefly reviewed. The concentrations found in common food sources and the effects of processing, or storage prior to consumption are discussed. Finally the factors that determine the bioavailability of L-AA and how it may be improved are considered, as well as the most important future research needs. # 2000 Society of Chemical Industry

Oxidative stress responses of the yeast Saccharomyces cerevisiae.

Abstract: All aerobically growing organisms suffer exposure to oxidative stress, caused by partially reduced forms of molecular oxygen, known as reactive oxygen species (ROS). These are highly reactive and capable of damaging cellular constituents such as DNA, lipids and proteins. Consequently, cells from many different organisms have evolved mechanisms to protect their components against ROS. This review concentrates on the oxidant defence systems of the budding yeast Saccharomyces cerevisiae, which appears to have a number of inducible adaptive stress responses to oxidants, such as H2O2, superoxide anion and lipid peroxidation products. The oxidative stress responses appear to be regulated, at least in part, at the level of transcription and there is considerable overlap between them and many diverse stress responses, allowing the yeast cell to integrate its response towards environmental stress.