H
H. Petursson
Researcher at deCODE genetics
Publications - 18
Citations - 2839
H. Petursson is an academic researcher from deCODE genetics. The author has contributed to research in topics: Schizophrenia (object-oriented programming) & Population. The author has an hindex of 12, co-authored 18 publications receiving 2708 citations.
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Journal ArticleDOI
Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma.
Gudmar Thorleifsson,Kristinn P. Magnusson,Patrick Sulem,G. Bragi Walters,Daniel F. Gudbjartsson,Hreinn Stefansson,Thorlakur Jonsson,Adalbjorg Jonasdottir,Aslaug Jonasdottir,Gerdur Stefansdottir,Gisli Masson,Gudmundur A. Hardarson,H. Petursson,Arsaell Arnarsson,Mehdi Motallebipour,Ola Wallerman,Claes Wadelius,Jeffrey R. Gulcher,Unnur Thorsteinsdottir,Augustine Kong,Fridbert Jonasson,Kari Stefansson +21 more
TL;DR: Two nonsynonymous SNPs in exon 1 of the gene LOXL1 explain the association with glaucoma, and the data suggest that they confer risk of XFG mainly through exfoliation syndrome (XFS).
Journal ArticleDOI
A genetic risk factor for periodic limb movements in sleep
Hreinn Stefansson,David B. Rye,Andrew A. Hicks,H. Petursson,Andres Ingason,Thorgeir E. Thorgeirsson,Stefan T Palsson,Thordur Sigmundsson,Albert P. Sigurdsson,Ingibjorg Eiriksdottir,Emilia Soebech,Donald L. Bliwise,Joseph M. Beck,Ami Rosen,Salina P. Waddy,Lynn Marie Trotti,Alex Iranzo,Madhav Thambisetty,Gudmundur A. Hardarson,Kristleifur Kristjansson,Larus J. Gudmundsson,Unnur Thorsteinsdottir,Augustine Kong,Jeffrey R. Gulcher,Daniel F. Gudbjartsson,Kari Stefansson +25 more
TL;DR: The inverse correlation of the variant with iron stores is consistent with the suspected involvement of iron depletion in the pathogenesis of the disease and is associated with susceptibility to periodic limb movements in sleep.
Journal ArticleDOI
Familial aggregation of Parkinson's disease in Iceland
Sigurlaug Sveinbjörnsdóttir,Andrew A. Hicks,Thorvaldur Jonsson,H. Petursson,Guğmundsson G,Mike Frigge,Augustine Kong,Gulcher,Kari Stefansson +8 more
TL;DR: Patients with Parkinson's disease, including a subgroup of 560 patients with late-onset disease (onset at >50 years of age), were significantly more related to each other than were subjects in matched groups of controls, and this relatedness extended beyond the nuclear family.
Journal ArticleDOI
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Andres Ingason,Andres Ingason,Dan Rujescu,Sven Cichon,Engilbert Sigurdsson,Thordur Sigmundsson,Olli Pietiläinen,Jacobine E. Buizer-Voskamp,Eric Strengman,Clyde Francks,Pierandrea Muglia,Arnaldur Gylfason,Omar Gustafsson,Pall I. Olason,Stacy Steinberg,Thomas Hansen,K.D. Jakobsen,Henrik B. Rasmussen,Ina Giegling,H.-J. Möller,Annette M. Hartmann,Caroline Crombie,Gillian Fraser,Neil Walker,Jan-Erik Lönnqvist,Jaana Suvisaari,Annamari Tuulio-Henriksson,Elvira Bramon,Lambertus A. Kiemeney,Barbara Franke,Robin M. Murray,Evangelos Vassos,Timothea Toulopoulou,Thomas W. Mühleisen,Sarah Tosato,Mirella Ruggeri,Srdjan Djurovic,Ole A. Andreassen,Zhongyang Zhang,Thomas Werge,Roel A. Ophoff,Roel A. Ophoff,M. Rietschel,Markus M. Nöthen,H. Petursson,Hreinn Stefansson,Leena Peltonen,Leena Peltonen,David A. Collier,Kari Stefansson,D. St Clair +50 more
TL;DR: It is concluded that duplications and perhaps also deletions of chromosome 16p13.1, previously reported to be associated with autism and MR, also confer risk of schizophrenia.
Journal ArticleDOI
CFH Y402H Confers Similar Risk of Soft Drusen and Both Forms of Advanced AMD
Kristinn P. Magnusson,Shan Duan,Shan Duan,Haraldur Sigurdsson,H. Petursson,Zhenglin Yang,Zhenglin Yang,Yu Zhao,Paul S. Bernstein,Jian Ge,Fridbert Jonasson,Einar Stefánsson,Gudleif Helgadottir,Norman A. Zabriskie,Thorlakur Jonsson,Asgeir Björnsson,Theodora Thorlacius,Palmi V. Jonsson,Gudmar Thorleifsson,Augustine Kong,Hreinn Stefansson,Kang Zhang,Kari Stefansson,Jeffrey R. Gulcher +23 more
TL;DR: The results suggest that CFH is a major risk factor of soft drusen, and additional genetic factors and/or environmental factors may be required for progression to advanced AMD.