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Hai Jun Deng
Researcher at Laboratory of Molecular Biology
Publications - 15
Citations - 5236
Hai Jun Deng is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 5 publications receiving 3951 citations.
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Journal ArticleDOI
Antibody responses to SARS-CoV-2 in patients with COVID-19.
Quanxin Long,Bai Zhong Liu,Hai Jun Deng,Gui Cheng Wu,Kun Deng,Yao Kai Chen,Pu Liao,Jing Fu Qiu,Yong Lin,Xue Fei Cai,Deqiang Wang,Yuan Hu,Ji Hua Ren,Ni Tang,Yin Yin Xu,Li Hua Yu,Zhan Mo,Fang Gong,Xiao-li Zhang,Wen Guang Tian,Li Hu,Xian Xiang Zhang,Jiang Lin Xiang,Hong Xin Du,Hua Wen Liu,Chun Hui Lang,Xiao He Luo,Shao Bo Wu,Xiao Ping Cui,Zheng Zhou,Man Man Zhu,Jing Wang,Cheng Jun Xue,Xiao Feng Li,Li Wang,Zhi Jie Li,Kun Wang,Chang Chun Niu,Qing Jun Yang,Xiaojun Tang,Yong Zhang,Xia Mao Liu,Jin Jing Li,De Chun Zhang,Fan Zhang,Liu Ping,Jun Yuan,Qin Li,Jie Li Hu,Juan Chen,Ailong Huang +50 more
TL;DR: It is suggested that SARS-CoV2-specific IgG or IgM seroconversion occurs within 20 days post symptom onset and may be helpful for the diagnosis of suspected patients with negative RT–PCR results and for the identification of asymptomatic infections.
Journal ArticleDOI
Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections.
Quanxin Long,Xiaojun Tang,Qiu Lin Shi,Qin Li,Hai Jun Deng,Jun Yuan,Jie Li Hu,Wei Xu,Yong Zhang,Fa Jin Lv,Kun Su,Fan Zhang,Jiang Gong,Bo Wu,Xia Mao Liu,Jin Jing Li,Jing Fu Qiu,Juan Chen,Ailong Huang +18 more
TL;DR: A cohort of asymptomatic patients infected with SARS-CoV-2 had significantly lower levels of virus-specific IgG antibodies compared to a cohort of age- and sex-matched symptomatic infected patients.
Posted ContentDOI
The D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity and decreases neutralization sensitivity to individual convalescent sera
Jie Hu,Chang Long He,Qingzhu Gao,Gui Ji Zhang,Xiao Xia Cao,Quanxin Long,Hai Jun Deng,Lu Yi Huang,Juan Chen,Kai Wang,Ni Tang,Ailong Huang +11 more
TL;DR: Using pseudovirus-based assay, it is found that S-D614 and S-G614 protein pseudotyped viruses share a common receptor, human angiotensin-converting enzyme 2 (ACE2), which could be blocked by recombinant ACE2 with the fused Fc region of human IgG1.
Posted ContentDOI
D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity
Jieli Hu,Changlong He,Qingzhu Gao,Guiji Zhang,Xuetao Cao,Quanxin Long,Hai Jun Deng,Lu-Yi Huang,Chen J,Kai Wang,Ni Tang,Ailong Huang +11 more
TL;DR: Using a pseudovirus-based assay, it is identified that S-D614 and S-G614 protein pseudotyped viruses share a common receptor, human angiotensin-converting enzyme 2 (ACE2), which could be blocked by recombinant ACE2 with the fused Fc region of human IgG1.