H
Haiping Mao
Researcher at Sun Yat-sen University
Publications - 111
Citations - 3031
Haiping Mao is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Peritoneal dialysis & Hazard ratio. The author has an hindex of 27, co-authored 97 publications receiving 2451 citations.
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Journal ArticleDOI
A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy
Maoyin Pang,Li Ma,Rujun Gong,Evelyn Tolbert,Haiping Mao,Murugavel Ponnusamy,Y. Eugene Chin,Haidong Yan,Lance D. Dworkin,Shougang Zhuang +9 more
TL;DR: Increased STAT3 activity mediates activation of renal interstitial fibroblasts and the progression of renal fibrosis, and inhibition of STAT3 signaling with S3I-201 may hold therapeutic potential for fibrotic kidney diseases.
Journal ArticleDOI
Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy
Maoyin Pang,Jagan Kothapally,Haiping Mao,Evelyn Tolbert,Murugavel Ponnusamy,Y. Eugene Chin,Shougang Zhuang +6 more
TL;DR: It is suggested that pharmacological HDAC inhibition may induce antifibrotic activity by inactivation of renal interstitial fibroblasts and inhibition of renal tubular cell death and STAT3 may mediate those actions of HDACs.
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Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis.
Huiyan Li,Xuan Peng,Yating Wang,Shirong Cao,Liping Xiong,Jinjin Fan,Yihan Wang,Shougang Zhuang,Xueqing Yu,Haiping Mao +9 more
TL;DR: Atg5-mediated autophagy in proximal epithelial cells is a critical host-defense mechanism that prevents renal fibrosis by blocking G2/M arrest, suggesting the regulation of cell cycle progression by ATG5 is Autophagy dependent.
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Prevalence and risk factors associated with chronic kidney disease in an adult population from southern China
Wei Chen,Wei-Qing Chen,Hui Wang,Xiuqing Dong,Qinghua Liu,Haiping Mao,Jiaqing Tan,Jianxiong Lin,Feiyu Zhou,Ning Luo,Huijuan He,Richard J. Johnson,Shu-Feng Zhou,Xueqing Yu +13 more
TL;DR: In the general adult population from southern China, 12.1% has either proteinuria, haematuria and/or reduced eGFR, indicating the presence of kidney damage, with an awareness of only 9.6%.
Journal ArticleDOI
Clinical outcome of hyperuricemia in IgA nephropathy: a retrospective cohort study and randomized controlled trial.
Yongjun Shi,Wei Chen,Diana Jalal,Zhibin Li,Wenfang Chen,Haiping Mao,Qiongqiong Yang,Richard J. Johnson,Xueqing Yu +8 more
TL;DR: Hyperuricemia predicts the progression of IgAN independently of baseline estimated glomerular filtration rate, and allopurinol may improve the control of blood pressure.