Hanna Tegel

TL;DR: In this paper, a map of the human tissue proteome based on an integrated omics approach that involves quantitative transcriptomics at the tissue and organ level, combined with tissue microarray-based immunohistochemistry, to achieve spatial localization of proteins down to the single-cell level.

TL;DR: A quantitative transcriptomics analysis (RNA-Seq) is used to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody-based profiling of the same tissues.

TL;DR: A subcellular map of the human proteome is presented to facilitate functional exploration of individual proteins and their role in human biology and disease and integrated into existing network models of protein-protein interactions for increased accuracy.

TL;DR: A new publicly available database containing, in the first version, ∼400,000 high resolution images corresponding to more than 700 antibodies toward human proteins, providing a knowledge base for functional studies and to allow queries about protein profiles in normal and disease tissues.

TL;DR: The findings imply an occupational risk for SARS-CoV-2 infection among healthcare workers and Continued measures are warranted to assure healthcare workers safety and reduce transmission from healthcare workers to patients and to the community.