Hannes Konrad Buchholz

TL;DR: In this paper, the thermodynamic difference between the two crystal forms is accessible by two cycles which give the eutectic composition in solution, and the sublimation cycle requires calculating the lattice energy and phonon frequencies of the crystal structures.

TL;DR: In this paper, a crystallization process was designed to purify artemisinin from fractions of a flash chromatography column effluent collected after injecting extracts of Artemisia annua leaves.

TL;DR: The calculated lattice energy differences between enantiopure and racemic crystal forms for a prototype set of chiral molecules are in good agreement with experimental results and allow the rationalization and computer‐aided design of chirus separation processes.

TL;DR: In this article, the potential of two-step enantioselective crystallization processes based on exploiting possible shifts of eutectic compositions in the phase diagrams is discussed, and the embedding of crystallization into hybrid processes capable of providing required initial enrichments is also discussed.

TL;DR: In this article, a detailed experimental analysis of phase transition thermodynamics of (S)-naproxen and (RS)-naphroxen is reported, where both sublimation and fusion enthalpies are adjusted to one reference temperature, T = 298 K, using measured heat capacities of the solid and the melt phase.