H
Hans A. Kestler
Researcher at University of Ulm
Publications - 351
Citations - 11671
Hans A. Kestler is an academic researcher from University of Ulm. The author has contributed to research in topics: Medicine & QRS complex. The author has an hindex of 50, co-authored 322 publications receiving 9994 citations. Previous affiliations of Hans A. Kestler include National Institutes of Health & École Normale Supérieure.
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Journal ArticleDOI
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Robert A. Scott,Laura J. Scott,Reedik Mägi,Letizia Marullo,Kyle J. Gaulton,Kyle J. Gaulton,Marika Kaakinen,Natalia Pervjakova,Tune H. Pers,Andrew D. Johnson,John D. Eicher,Anne U. Jackson,Teresa Ferreira,Yeji Lee,Clement Ma,Valgerdur Steinthorsdottir,Gudmar Thorleifsson,Lu Qi,Lu Qi,Natalie R. van Zuydam,Natalie R. van Zuydam,Anubha Mahajan,Han Chen,Peter Almgren,B F Voight,Harald Grallert,Martina Müller-Nurasyid,Janina S. Ried,Nigel W. Rayner,Nigel W. Rayner,Nigel W. Rayner,Neil Robertson,Neil Robertson,Lennart C. Karssen,Elisabeth M. van Leeuwen,Sara M. Willems,Sara M. Willems,Christian Fuchsberger,Phoenix Kwan,Tanya M. Teslovich,Pritam Chanda,Man Li,Yingchang Lu,Christian Dina,Dorothée Thuillier,Loic Yengo,Longda Jiang,Thomas Sparsø,Hans A. Kestler,Hans A. Kestler,Himanshu Chheda,Lewin Eisele,Stefan Gustafsson,Mattias Frånberg,Mattias Frånberg,Mattias Frånberg,Rona J. Strawbridge,Rafn Benediktsson,Astradur B. Hreidarsson,Augustine Kong,Gunnar Sigurðsson,Nicola D. Kerrison,Jian'an Luan,Liming Liang,Thomas Meitinger,Michael Roden,Barbara Thorand,Tõnu Esko,Tõnu Esko,Tõnu Esko,Evelin Mihailov,Caroline S. Fox,Ching-Ti Liu,Denis Rybin,Bo Isomaa,Valeriya Lyssenko,Tiinamaija Tuomi,David Couper,James S. Pankow,Niels Grarup,Christian Theil Have,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,Allan Linneberg,Allan Linneberg,Marilyn C. Cornelis,Rob M. van Dam,Rob M. van Dam,David J. Hunter,Peter Kraft,Qi Sun,Qi Sun,Sarah Edkins,Katharine R. Owen,Katharine R. Owen,John R. B. Perry,Andrew R. Wood,Eleftheria Zeggini,Juan Tajes-Fernandes,Gonçalo R. Abecasis,Lori L. Bonnycastle,Peter S. Chines,Heather M. Stringham,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Leena Kinnunen,Leena Kinnunen,Leena Kinnunen,Bengt Sennblad,Bengt Sennblad,Thomas W. Mühleisen,Markus M. Nöthen,Sonali Pechlivanis,Damiano Baldassarre,Karl Gertow,Steve E. Humphries,Elena Tremoli,Norman Klopp,Julia Meyer,Gerald Steinbach,Roman Wennauer,Johan G. Eriksson,Satu Mӓnnistö,Leena Peltonen,Emmi Tikkanen,Guillaume Charpentier,E. Eury,Stéphane Lobbens,Bruna Gigante,Karin Leander,Olga McLeod,Erwin P. Bottinger,Omri Gottesman,Douglas M. Ruderfer,Matthias Blüher,Peter Kovacs,Anke Tönjes,Nisa M. Maruthur,Chiara Scapoli,Raimund Erbel,Karl-Heinz Jöckel,Susanne Moebus,Ulf de Faire,Anders Hamsten,Michael Stumvoll,Panagiotis Deloukas,Panagiotis Deloukas,Peter Donnelly,Peter Donnelly,Timothy M. Frayling,Andrew T. Hattersley,Samuli Ripatti,Veikko Salomaa,Nancy L. Pedersen,Bernhard O. Boehm,Richard N. Bergman,Francis S. Collins,Karen L. Mohlke,Jaakko Tuomilehto,Torben Hansen,Torben Hansen,Oluf Pedersen,Inês Barroso,Inês Barroso,Lars Lannfelt,Erik Ingelsson,Erik Ingelsson,Lars Lind,Cecilia M. Lindgren,Cecilia M. Lindgren,Stéphane Cauchi,Philippe Froguel,Philippe Froguel,Ruth J. F. Loos,Beverley Balkau,Beverley Balkau,Heiner Boeing,Paul W. Franks,Paul W. Franks,Aurelio Barricarte Gurrea,Domenico Palli,Yvonne T. van der Schouw,David Altshuler,Leif Groop,Leif Groop,Claudia Langenberg,Nicholas J. Wareham,Eric J.G. Sijbrands,Cornelia M. van Duijn,Jose C. Florez,Jose C. Florez,James B. Meigs,James B. Meigs,Eric Boerwinkle,Eric Boerwinkle,Christian Gieger,Konstantin Strauch,Andres Metspalu,Andrew D. Morris,Colin N. A. Palmer,Frank B. Hu,Frank B. Hu,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Josée Dupuis,Andrew P. Morris,Michael Boehnke,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Inga Prokopenko,Inga Prokopenko,Inga Prokopenko +216 more
TL;DR: This article conducted a meta-analysis of genome-wide association data from 26,676 T2D case and 132,532 control subjects of European ancestry after imputation using the 1000 Genomes multiethnic reference panel.
Journal ArticleDOI
Sequelae of acute myocardial infarction regarding cardiac structure and function and their prognostic significance as assessed by magnetic resonance imaging.
Vinzenz Hombach,Olaf Grebe,Nico Merkle,Sebastian Waldenmaier,Martin Höher,Matthias Kochs,Jochen Wöhrle,Hans A. Kestler +7 more
TL;DR: MRI is a highly sensitive and reliable tool to detect morphologic and functional sequelae of AMI providing baseline MRI parameters with relevant predictive power for LV adverse remodelling and occurrence of MACE.
Journal ArticleDOI
Three learning phases for radial-basis-function networks
TL;DR: It can be observed that the performance of RBF classifiers trained with two-phase learning can be improved through a third backpropagation-like training phase of the RBF network, adapting the whole set of parameters (RBF centers, scaling parameters, and output layer weights) simultaneously.
Journal ArticleDOI
MYC stimulates EZH2 expression by repression of its negative regulator miR-26a.
Sandrine Sander,Lars Bullinger,Kay Klapproth,Katja Fiedler,Hans A. Kestler,Thomas F. E. Barth,Peter Möller,Stephan Stilgenbauer,Jonathan R. Pollack,Thomas Wirth +9 more
TL;DR: It is shown that ectopic expression of miR-26a influenced cell cycle progression by targeting the bona fide oncogene EZH2, a Polycomb protein and global regulator of gene expression yet unknown to be regulated by miRNAs, thereby vitally contributing to MYC-induced lymphomagenesis.
Journal ArticleDOI
BoolNet—an R package for generation, reconstruction and analysis of Boolean networks
TL;DR: BoolNet efficiently integrates methods for synchronous, asynchronous and probabilistic BNs, and includes reconstructing networks from time series, generating random networks, robustness analysis via perturbation, Markov chain simulations, and identification and visualization of attractors.