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Author

Hans-Joachim Santel

Bio: Hans-Joachim Santel is an academic researcher from Bayer. The author has contributed to research in topics: Alkyl & Alkoxy group. The author has an hindex of 36, co-authored 604 publications receiving 5399 citations.
Topics: Alkyl, Alkoxy group, Aryl, Thio-, Trifluoromethyl


Papers
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Patent
29 Apr 1996
TL;DR: In this paper, several processes for preparing said compounds and their use as pesticides and herbicides are discussed, as well as several processes to prepare them and their application as herbicides.
Abstract: New compounds have the formula (I), in which X stands for halogen, Y stands for halogen or alkyl and Z stands for halogen or alkyl, provided that one of the residues Y and Z always stands for halogen and the other for alkyl, and Het stands for one of the groups (1), (2), (3), (4), (5) or (6), in which A, B, D, and G have the meanings given in the description. Also disclosed are several processes for preparing said compounds and their use as pesticides and herbicides.

148 citations

Patent
31 Jan 1996
TL;DR: The present invention relates to novel compounds of the formula (I) in which X, Y and Z have the meanings given in the specification and Het stands for one of the groups (1), (2), (3), (4), (5) or (6).
Abstract: The present invention relates to novel compounds of the formula (I) in which X, Y and Z have the meanings given in the specification and Het stands for one of the groups (1), (2), (3), (4), (5) or (6), in which A, B, D and G have the meanings given in the specification, several process for their production and their use as pesticides and herbicides.

138 citations

Patent
TL;DR: In this paper, the authors proposed novel compounds of formula (I) in which: X stands for alkyl; Y stands for halogen or alkyls; Z stands for either halogen and/or alkaline; and Het stands for one of the groups (1-6) shown, in which A, B, D and G have the meanings indicated in the description.
Abstract: The invention concerns novel compounds of formula (I) in which: X stands for alkyl; Y stands for halogen or alkyl; Z stands for halogen or alkyl, a condition being that one of the groups Y and Z always stands for halogen and the other for alkyl; and Het stands for one of the groups (1-6) shown, in which A, B, D and G have the meanings indicated in the description. The invention also pertains to several processes for producing these compounds and the use of the compounds as pest-control agents and herbicides.

138 citations

Patent
17 Jun 1996
TL;DR: In this article, a novel phenyl-substituted cyclic keto-enols of formula (I) in which Het stands for one of the groups shown in which A, B, D, G, X, Y and Z have the meanings indicated in the description.
Abstract: The invention concerns novel phenyl-substituted cyclic keto-enols of formula (I) in which Het stands for one of the groups shown in which A, B, D, G, X, Y and Z have the meanings indicated in the description. Also disclosed are several processes and intermediate products for producing these compounds and their use as pest-control agents and herbicides.

137 citations

Patent
25 Oct 1993
TL;DR: In this paper, a new 1-H-3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) in which A and H together with the carbon atom to which they are bonded represent a substituted cycle was introduced.
Abstract: The invention relates to new 1-H-3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) in which A and H together with the carbon atom to which they are bonded represent a substituted cycle, X represents alkyl, halogen or alkoxy, Y represents hydrogen, alkyl, halogen, alkoxy or halogenoalkyl, Z represents alkyl, halogen or alkoxy, n represents 0, 1, 2 or 3, G represents hydrogen (a) or the groups E represents a metal ion equivalent or an ammonium ion, L and M represents oxygen and/or sulphur, R1 represents in each case optionally halogen-substituted alkyl, alkenyl, alkoxyalkyl, alkylthio-alkyl, polyalkoxyalkyl or cycloalkyl, which can be interrupted by hetero atoms, optionally substituted phenyl, optionally substituted phenylalkyl, substituted hetaryl, substituted phenoxyalkyl or substituted hetaryloxyalkyl, R2 represents in each case optionally halogen-substituted alkyl, alkenyl, alkoxyalkyl, polyalkoxy-alkyl or in each case optionally substituted phenyl or benzyl, R3, R4 and R5 independently of one another represent in each case optionally halogen-substituted alkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkenylthio, cycloalkylthio and in each case optionally substituted phenyl, phenoxy or phenylthio, R6 and R7 independently of one another represent hydrogen, in each case optionally halogen-substituted alkyl, alkenyl, alkoxy, alkoxyalkyl, or represent optionally substituted phenyl, optionally substituted benzyl, or, together with the adjacent N-atom, represent a cycle which is optionally interrupted by oxygen or sulphur, to processes for their preparation, and to their use as pesticides.

137 citations


Cited by
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Patent
01 Feb 1999
TL;DR: An adaptive interface for a programmable system, for predicting a desired user function, based on user history, as well as machine internal status and context, is presented for confirmation by the user, and the predictive mechanism is updated based on this feedback as mentioned in this paper.
Abstract: An adaptive interface for a programmable system, for predicting a desired user function, based on user history, as well as machine internal status and context. The apparatus receives an input from the user and other data. A predicted input is presented for confirmation by the user, and the predictive mechanism is updated based on this feedback. Also provided is a pattern recognition system for a multimedia device, wherein a user input is matched to a video stream on a conceptual basis, allowing inexact programming of a multimedia device. The system analyzes a data stream for correspondence with a data pattern for processing and storage. The data stream is subjected to adaptive pattern recognition to extract features of interest to provide a highly compressed representation that may be efficiently processed to determine correspondence. Applications of the interface and system include a video cassette recorder (VCR), medical device, vehicle control system, audio device, environmental control system, securities trading terminal, and smart house. The system optionally includes an actuator for effecting the environment of operation, allowing closed-loop feedback operation and automated learning.

1,182 citations

PatentDOI
TL;DR: In this article, the imidazo[1,2-a]pyrimidine derivatives are used for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET.
Abstract: The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

1,135 citations

Journal ArticleDOI
TL;DR: The purpose of this review is to underscore and illustrate those scientific problems unique to the discovery and optimization of novel antibacterial agents that have adversely affected the output of the effort.
Abstract: Summary: The discovery of novel small-molecule antibacterial drugs has been stalled for many years. The purpose of this review is to underscore and illustrate those scientific problems unique to the discovery and optimization of novel antibacterial agents that have adversely affected the output of the effort. The major challenges fall into two areas: (i) proper target selection, particularly the necessity of pursuing molecular targets that are not prone to rapid resistance development, and (ii) improvement of chemical libraries to overcome limitations of diversity, especially that which is necessary to overcome barriers to bacterial entry and proclivity to be effluxed, especially in Gram-negative organisms. Failure to address these problems has led to a great deal of misdirected effort.

1,107 citations

Patent
28 Jul 2006
TL;DR: In this article, a medical sensor is adapted to account for factors that cause irregularities in pulse oximetry measurements or other spectrophotemetric measurements using surface features that reduce the amount of outside light or shunted light that impinge the detecting elements of the sensor.
Abstract: A medical sensor may be adapted to account for factors that cause irregularities in pulse oximetry measurements or other spectrophotemetric measurements. Sensors are provided with surface features that reduce the amount of outside light or shunted light that impinge the detecting elements of the sensor. The sensor is adapted to reduce the effect of outside light or shunted light on pulse oximetry measurements.

580 citations

Patent
19 Dec 2001
TL;DR: In this article, the pyrazole compounds of formula (IV) were described for protein kinase inhibitors, especially as inhibitors of aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzehimer's disease.
Abstract: This invention describes novel pyrazole compounds of formula (IV) wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; R?x and Ry? are independently selected from T-R3, or taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-8 membered ring having 1-3 ring heteroatoms selected from oxygen, sulfur, or nitrogen; and R2, R2', and T, and R3 are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzehimer's disease.

470 citations