H
Hans-Peter Lenhof
Researcher at Saarland University
Publications - 170
Citations - 6982
Hans-Peter Lenhof is an academic researcher from Saarland University. The author has contributed to research in topics: Cancer & Macromolecular docking. The author has an hindex of 44, co-authored 164 publications receiving 6046 citations. Previous affiliations of Hans-Peter Lenhof include Max Planck Society.
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Journal ArticleDOI
Novel immunogenic antigens increase classification accuracy in meningioma to 93.84
Nicole Ludwig,Andreas Keller,Sabrina Heisel,Petra Leidinger,Stefanie Rheinheimer,Claudia Andres,Bernhard Stephan,Wolf-Ingo Steudel,Erich Donauer,Norbert Graf,Bernhard Burgeth,Joachim Weickert,Hans-Peter Lenhof,Eckart Meese +13 more
TL;DR: The results demonstrate that the accuracy of a serum‐based diagnostic can be readily and considerably improved by screening extended sets of proteins.
Journal ArticleDOI
RegulatorTrail: a web service for the identification of key transcriptional regulators.
Tim Kehl,Lara Schneider,Florian Schmidt,Daniel Stöckel,Nico Gerstner,Christina Backes,Eckart Meese,Andreas Keller,Marcel H. Schulz,Hans-Peter Lenhof +9 more
TL;DR: RegulatorTrail is presented, a web service that provides rich functionality for the identification and prioritization of key transcriptional regulators that have a strong impact on natural and pathogenic processes, and successfully identified regulators that might explain the increased malignancy in metastatic melanoma compared to primary tumors, as well as important regulators in macrophages.
Proceedings ArticleDOI
ProteinScanAR - An Augmented Reality Web Application for High School Education in Biomolecular Life Sciences
Stefan Nickels,Hienke Sminia,Sabine C. Mueller,Bas Kools,Anna Katharina Dehof,Hans-Peter Lenhof,Andreas Hildebrandt +6 more
TL;DR: This work presents ProteinScanAR, an augmented reality framework for biomolecular education that allows connecting virtual and real worlds intuitively, and thus enables focusing on the scientific or educational content.
Journal ArticleDOI
Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase
Stefan Tenzer,Petra Leidinger,Christina Backes,Hanno Huwer,Andreas Hildebrandt,Hans-Peter Lenhof,Tanja Wesse,Andre Franke,Eckart Meese,Andreas Keller +9 more
TL;DR: Principal Component Analysis provided evidence that not only cancer from control tissue but also tissue from adenocarcinoma and SCC can be differentiated.
Journal ArticleDOI
Combination of Autoantibody Signature with PSA Level Enables a Highly Accurate Blood-Based Differentiation of Prostate Cancer Patients from Patients with Benign Prostatic Hyperplasia.
Petra Leidinger,Andreas Keller,Lisa Milchram,Christian Harz,Martin Hart,Angelika Werth,Hans-Peter Lenhof,Andreas Weinhäusel,Bastian Keck,Bernd Wullich,Nicole Ludwig,Eckart Meese +11 more
TL;DR: A minimally invasive serological method to reduce false positive results in detection of prostate cancer and according to PSA screening to distinguish men with prostate cancer from men with benign prostatic hyperplasia is provided.