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TL;DR: Initial cellular evaluations supports the view that compound collections based on natural-product-inspired scaffolds constructed with complex stereochemistry, and decorated with assorted substituents, will be a rich source of compounds with diverse bioactivity.

TL;DR: A one-pot, twelve-step cascade reaction sequence that includes nine different reactions and two opposing kinds of organocatalysis is reported that transforms readily available substrates into complex indoloquinolizines that resemble the core tetracyclic scaffold of numerous polycyclic indole alkaloids.

TL;DR: A one pot 4–7 step synthesis of mono-, bi-, and tricyclic oxepanes that resemble the core scaffolds of numerous NPs with diverse bioactivities and makes productive use of polymer-immobilized scavenger reagents is developed.

TL;DR: The crystal and molecular structure of hexaphenyl distannane has been determined from 2939 independent reflexes by FOURIER analyses and refined three dimensionally by least-squares-methods as mentioned in this paper.

TL;DR: An enantioselectively catalyzed tandem synthesis of structurally and stereochemically complex molecules that forms four carbon-carbon bonds and sets eight stereocenters with high regio-, diastereo- and enantiOSElectivity is developed.