H
Hans Thoenen
Researcher at Max Planck Society
Publications - 225
Citations - 44313
Hans Thoenen is an academic researcher from Max Planck Society. The author has contributed to research in topics: Nerve growth factor & Neurotrophic factors. The author has an hindex of 104, co-authored 225 publications receiving 43704 citations. Previous affiliations of Hans Thoenen include St George's Hospital.
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Journal ArticleDOI
Neurotrophins and neuronal plasticity.
TL;DR: A role for NTs as selective retrograde messengers that regulate synaptic efficacy is suggested, based on evidence that NT synthesis is rapidly regulated by neuronal activity and that NTs are released in an activity-dependent manner from neuronal dendrites.
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Purification of a new neurotrophic factor from mammalian brain.
TL;DR: This factor is the first neurotrophic factor to be purified since NGF, from which it is clearly distinguished because it has different antigenic and functional properties.
Journal ArticleDOI
Molecular cloning and expression of brain-derived neurotrophic factor.
Joachim Leibrock,Friedrich Lottspeich,Hohn Andreas,Magdalena Hofer,Bastian Hengerer,Piotr Masiakowski,Hans Thoenen,Yves-Alain Barde +7 more
TL;DR: The full primary structure of brain-derived neurotrophic factor is reported and it is established that these two neurotrophic factors are related both functionally and structurally.
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Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.
TL;DR: It is suggested that BDNF might have a functional role in the expression of LTP in the hippocampus, and the magnitude of the potentiation, as well as the percentage of cases in which LTP could be induced successfully, was clearly affected.