H
Hans-Ulrich Häring
Researcher at University of Tübingen
Publications - 89
Citations - 13407
Hans-Ulrich Häring is an academic researcher from University of Tübingen. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 51, co-authored 89 publications receiving 11784 citations. Previous affiliations of Hans-Ulrich Häring include Ludwig Maximilian University of Munich.
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Journal ArticleDOI
Identification and characterization of metabolically benign obesity in humans.
Norbert Stefan,Konstantinos Kantartzis,Jürgen Machann,Fritz Schick,Claus Thamer,Kilian Rittig,Bernd Balletshofer,Fausto Machicao,Andreas Fritsche,Hans-Ulrich Häring +9 more
TL;DR: A metabolically benign obesity that is not accompanied by insulin resistance and early atherosclerosis exists in humans and ectopic fat in the liver may be more important than visceralfat in the determination of such a beneficial phenotype in obesity.
Journal ArticleDOI
Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
Anna Floegel,Norbert Stefan,Zhonghao Yu,Kristin Mühlenbruch,Dagmar Drogan,Hans-Georg Joost,Andreas Fritsche,Hans-Ulrich Häring,Martin Hrabě de Angelis,Annette Peters,Michael Roden,Cornelia Prehn,Rui Wang-Sattler,Thomas Illig,Matthias B. Schulze,Jerzy Adamski,Heiner Boeing,Tobias Pischon +17 more
TL;DR: The data indicate that metabolic alterations, including sugar metabolites, amino acids, and choline-containing phospholipids, are associated early on with a higher risk of T2D.
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Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB
Angelika Bierhaus,Stephan Schiekofer,Stephan Schiekofer,Markus Schwaninger,Martin Andrassy,Martin Andrassy,Per M. Humpert,Jiang Chen,Jiang Chen,Mei Hong,Thomas Luther,Thomas Henle,Ingrid Klöting,Michael Morcos,Marion A. Hofmann,Hans J. Tritschler,Bernd Weigle,Michael Kasper,Mark A. Smith,George Perry,Ann Marie Schmidt,David M. Stern,Hans-Ulrich Häring,Erwin Schleicher,Peter P. Nawroth,Peter P. Nawroth +25 more
TL;DR: Data demonstrate that ligands of RAGE can induce sustained activation of NF-kappaB as a result of increased levels of de novo synthesized NF-KappaBp65 overriding endogenous negative feedback mechanisms and thus might contribute to the persistent NF- kappaB activation observed in hyperglycemia and possibly other chronic diseases.
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Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.
Stephan Jacob,Jürgen Machann,Kristian Rett,Klaus Brechtel,A. Volk,Walter Renn,E. Maerker,Stephan Matthaei,Fritz Schick,Claus D. Claussen,Hans-Ulrich Häring +10 more
TL;DR: In these well-matched groups of lean subjects, IMCL is increased in insulin-resistant offspring of type 2 diabetic subjects when compared with an insulin-sensitive group matched for age, BMI, body fat distribution, percent body fat, and degree of physical fitness.
Journal ArticleDOI
T-helper-1-cell cytokines drive cancer into senescence
Heidi Braumüller,Thomas Wieder,Ellen Brenner,Sonja Aßmann,Matthias Hahn,Mohammed Alkhaled,Karin Schilbach,Frank Essmann,Manfred Kneilling,Christoph M. Griessinger,Felicia Ranta,Susanne Ullrich,Ralph Mocikat,Kilian Braungart,Tarun Mehra,Birgit Fehrenbacher,Julia Berdel,Heike Niessner,Friedegund Meier,Maries van den Broek,Hans-Ulrich Häring,Rupert Handgretinger,Leticia Quintanilla-Martinez,Falko Fend,Marina Pesic,Jürgen Bauer,Lars Zender,Martin Schaller,Klaus Schulze-Osthoff,Martin Röcken +29 more
TL;DR: The combined action of the T-helper-1-cell cytokines IFN-γ and tumour necrosis factor (TNF) directly induces permanent growth arrest in cancers, a general mechanism for arresting cancer progression.