Hao Wu

TL;DR: Evidence is provided that rare pathogenic variants in the SPINK1, PRSS1, CTRC, and CFTR genes significantly influence the age of onset and clinical outcomes of CP.

TL;DR: A hybrid allele between the carboxyl ester lipase gene (CEL) and its pseudogene, CELP (called CEL-HYB), generated by nonallelic homologous recombination between CEL intron 10 andCELP intron10', was found to increase susceptibility to chronic pancreatitis in a case-control study of patients of European ancestry, but it was failed to detect in 3 independent cohorts from China, Japan, and India.

TL;DR: Intravenous administration of octreotide for 72 hours in the early stage of AP could prevent the development of SAP effectively in obese patients by raising plasma somatostatin to a normal level and reducing circulating cytokines.

TL;DR: The first video capsule endoscope was introduced in 2001 by Iddan as a new tool for the investigation of the small bowel and various studies have shown the potential of this minimally invasive technique to improve diagnostic outcome s among a variety of gastrointestinal (GI) conditions.

TL;DR: Target next‐generation sequencing of the CPA1 gene was performed in 1,112 Han Chinese idiopathic chronic pancreatitis patients and 1,580 controls, and no significant association was noted with ICP irrespective of whether all rare variants or functionally impaired variants were considered.