H
Harold Brem
Researcher at New York University
Publications - 84
Citations - 9512
Harold Brem is an academic researcher from New York University. The author has contributed to research in topics: Wound healing & Diabetic foot. The author has an hindex of 36, co-authored 83 publications receiving 8304 citations. Previous affiliations of Harold Brem include Columbia University & Winthrop University.
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Growth factors and cytokines in wound healing.
TL;DR: A review of the specific roles of these growth factors and cytokines during wound healing can be found in this article, where patients are treated by three growth factors: PDGF-BB, bFGF, and GM-CSF.
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Cellular and molecular basis of wound healing in diabetes
Harold Brem,Marjana Tomic-Canic +1 more
TL;DR: In this issue of the JCI, Gallagher and colleagues demonstrate that in diabetic mice, hyperoxia enhances the mobilization of circulating endothelial progenitor cells (EPCs) from the bone marrow to the peripheral circulation, resulting in accelerated wound healing.
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The role of vascular endothelial growth factor in wound healing.
TL;DR: Experimental data supports the hypothesis that VEGF stimulates epithelialization and collagen deposition in a wound, but likely promotes collagen deposition and epithelization as well, and stimulates wound healing through angiogenesis.
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Molecular pathogenesis of chronic wounds: The role of β-catenin and c-myc in the inhibition of epithelialization and wound healing
Olivera Stojadinovic,Harold Brem,Constantinos Vouthounis,Brian Lee,John T. Fallon,Michael R. Stallcup,Ankit Merchant,Robert D. Galiano,Marjana Tomic-Canic +8 more
TL;DR: It is concluded that activation of the beta-catenin/c-myc pathway(s) contributes to impaired healing by inhibiting keratinocyte migration and altering their differentiation.
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High cost of stage IV pressure ulcers
Harold Brem,Jason Maggi,David M. Nierman,Linda Rolnitzky,David Bell,Robert C. Rennert,Michael S. Golinko,Alan Yan,Courtney Lyder,Bruce C. Vladeck +9 more
TL;DR: The costs incurred from stage IV pressure ulcers are much greater than previously estimated and have the potential to eradicate enormous pain and suffering, save thousands of lives, and reduce health care expenditures by millions of dollars.