Heidi Abrahamse

TL;DR: The dual-specificity of PDT relies on accumulation of the PS in diseased tissue and also on localized light delivery, and future directions include photochemical internalization, genetically encoded protein PSs, theranostics, two-photon absorption PDT, and sonodynamic therapy using ultrasound.

TL;DR: A broad review of different parameters used and mechanisms instituted in PDT such as photosensitizers (PS), photochemistry and photophysics, cellular localization, cellular signaling, cell metabolism and modes of cell death that operate on a cellular level, as well as photoensitizer pharmacokinetics, biodistribution, tumor localization and mode of tumor destruction.

TL;DR: This study aimed to establish cellular responses to Helium‐Neon (632.8 nm) laser irradiation using different laser fluences with a single exposure on 2 consecutive days on normal and wounded human skin fibroblasts.

TL;DR: Results show that the correct energy density or fluence (J/cm(2) and number of exposures can stimulate cellular responses of wounded fibroblasts and promote cell migration and cell proliferation by stimulating mitochondrial activity and maintaining viability without causing additional stress or damage to the wounded cells.

TL;DR: PBM induced a stimulatory effect on various CAMs namely cadherins, integrins, selectins and immunoglobulins, and hence may be used as a complementary therapy in advancing treatment of non-healing diabetic ulcers.