H
Hélcio Silva dos Santos
Researcher at State University of Ceará
Publications - 167
Citations - 1334
Hélcio Silva dos Santos is an academic researcher from State University of Ceará. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 15, co-authored 112 publications receiving 832 citations. Previous affiliations of Hélcio Silva dos Santos include Universidade Estadual do Vale do Acaraú & Federal University of Ceará.
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Journal ArticleDOI
Casbane diterpene as a promising natural antimicrobial agent against biofilm-associated infections.
Victor Alves Carneiro,Hélcio Silva dos Santos,Francisco Vassiliepe Sousa Arruda,Paulo Nogueira Bandeira,Maria Rose Jane R. Albuquerque,Maria Olívia Pereira,Mariana Henriques,Benildo Sousa Cavada,Edson Holanda Teixeira +8 more
TL;DR: It was found that CD possessed biocidal and biostatic activity against the majority of the species screened, with minimal active concentrations ranging between 125 and 500 µg/mL.
Journal ArticleDOI
Antimicrobial and antibiofilm action of Casbane Diterpene from Croton nepetaefolius against oral bacteria
Nairley Cardoso Sá,Theodora Thays Arruda Cavalcante,Amanda Ximenes Araújo,Hélcio Silva dos Santos,Maria Rose Jane R. Albuquerque,Paulo Nogueira Bandeira,Rodrigo Maranguape Silva da Cunha,Benildo Sousa Cavada,Edson Holanda Teixeira +8 more
TL;DR: The compound CD can be considered as a promising molecule for the treatment against oral pathogens responsible for dental biofilm and shows antimicrobial effect on planktonic forms and biofilms of oral pathogens.
Journal ArticleDOI
Chemical composition, antioxidant, antifungal and hemolytic activities of essential oil from Baccharis trinervis (Lam.) Pers. (Asteraceae)
Antonio Carlos Nogueira Sobrinho,Elnatan Bezerra de Souza,Marcos Fábio Gadelha Rocha,Maria Rose Jane R. Albuquerque,Paulo Nogueira Bandeira,Hélcio Silva dos Santos,Carolina Sidrim de Paula Cavalcante,Samuel Souza Oliveira,Priscila Rodrigues Aragão,Selene Maia de Morais,Raquel Oliveira dos Santos Fontenelle +10 more
TL;DR: The essential oil inhibited growth of dermatophytic fungi and enhanced the effect of ketoconazole via synergistic activity and antioxidant and antimicrobial potential are demonstrated.
Journal ArticleDOI
Amyrin esters induce cell death by apoptosis in HL-60 leukemia cells.
Francisco W.A. Barros,Paulo Nogueira Bandeira,Daisy Jereissati Barbosa Lima,Assuero Silva Meira,Silvana S. de Farias,Maria Rose Jane R. Albuquerque,Hélcio Silva dos Santos,Telma L. G. Lemos,Manoel Odorico de Morais,Letícia V. Costa-Lotufo,Cláudia Pessoa +10 more
TL;DR: The results indicate that the cytotoxicity of 3a/3b involves the induction of cell death by apoptosis.
Journal ArticleDOI
Chemical Composition and Antimicrobial Effectiveness of Ocimum gratissimum L. Essential Oil Against Multidrug-Resistant Isolates of Staphylococcus aureus and Escherichia coli.
Ramaiana Soares Melo,Águida Maria Albuquerque Azevedo,Antônio Mateus Gomes Pereira,Renan Rhonalty Rocha,Rafaela Mesquita Bastos Cavalcante,Maria Nágila Carneiro Matos,Pedro Henrique Ribeiro Lopes,Geovany Amorim Gomes,Tigressa Helena Soares Rodrigues,Hélcio Silva dos Santos,Izabelly Linhares Ponte,Renata Albuquerque Costa,Gabriel Sousa Brito,Francisco Eduardo Aragão Catunda Júnior,Victor Alves Carneiro,Victor Alves Carneiro +15 more
TL;DR: EOOG has relevant potential as a natural alternative to treat infections caused by multiresistant strains and was verified against isolates of Staphylococcus aureus and Escherichia coli, using four strains for each species.