H
Helen Patterson
Researcher at Cardiff University
Publications - 8
Citations - 5260
Helen Patterson is an academic researcher from Cardiff University. The author has contributed to research in topics: Prostate cancer & Sexual function. The author has an hindex of 6, co-authored 7 publications receiving 4607 citations.
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Journal ArticleDOI
Abiraterone and Increased Survival in Metastatic Prostate Cancer
Johann S. de Bono,Christopher J. Logothetis,Arturo Molina,Karim Fizazi,Scott North,Luis Chu,Kim N. Chi,Robert Jones,Oscar B. Goodman,Fred Saad,John Staffurth,Paul N. Mainwaring,S. J. Harland,Thomas W. Flaig,Thomas E. Hutson,Tina Cheng,Helen Patterson,John D. Hainsworth,Charles J. Ryan,Cora N. Sternberg,Susan Ellard,Aude Flechon,Mansoor N. Saleh,Mark C. Scholz,Eleni Efstathiou,Andrea Zivi,Diletta Bianchini,Yohann Loriot,Nicole Chieffo,Thian Kheoh,Christopher M. Haqq,Howard I. Scher +31 more
TL;DR: The inhibition of androgen biosynthesis by abiraterone acetate prolonged overall survival among patients with metastatic castration-resistant prostate cancer who previously received chemotherapy.
Journal ArticleDOI
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
David P. Dearnaley,Isabel Syndikus,Helen Mossop,Vincent Khoo,Alison Birtle,D. Bloomfield,John Graham,Peter Kirkbride,John P Logue,Zafar Malik,Julian Money-Kyrle,Joe M. O'Sullivan,Miguel Panades,Chris Parker,Helen Patterson,Christopher D Scrase,John Staffurth,Andrew Stockdale,Jean Tremlett,M. Bidmead,Helen Mayles,O. Naismith,C. South,Annie Gao,Clare Cruickshank,Shama Hassan,Julia Pugh,Clare Griffin,Emma Hall +28 more
TL;DR: Hypofractionated radiotherapy using 60 Gy in 20 fractions is non-inferior to conventional fractionation using 74 Gy in 37 fractions and is recommended as a new standard of care for external-beam radiotherapy of localised prostate cancer after 5 years follow-up.
Journal ArticleDOI
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled trial
David P. Dearnaley,Isabel Syndikus,Georges Sumo,M. Bidmead,D. Bloomfield,Catharine H. Clark,Annie Gao,Shama Hassan,Alan Horwich,Robert Huddart,Vincent Khoo,Peter Kirkbride,Helen Mayles,P. Mayles,O. Naismith,Chris Parker,Helen Patterson,Martin J. Russell,Christopher D Scrase,C. South,John Staffurth,Emma Hall +21 more
TL;DR: A pre-planned preliminary safety analysis of side-effects in stages 1 and 2 of a randomised trial comparing standard and hypofractionated radiotherapy seems equally well tolerated as conventionally fractionated treatment at 2 years.
Journal ArticleDOI
Hypofractionated radiotherapy versus conventionally fractionated radiotherapy for patients with intermediate-risk localised prostate cancer: 2-year patient-reported outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
Anna Wilkins,Helen Mossop,Isabel Syndikus,Vincent Khoo,D. Bloomfield,Chris Parker,John P Logue,Christopher D Scrase,Helen Patterson,Alison Birtle,John Staffurth,Zafar Malik,Miguel Panades,C. Eswar,John Graham,Martin J. Russell,Peter Kirkbride,Joe M. O'Sullivan,Annie Gao,Clare Cruickshank,Clare Griffin,David P. Dearnaley,Emma Hall +22 more
TL;DR: The incidence of patient-reported bowel symptoms was low and similar between patients in the 74 Gy control group and the hypofractionated groups up to 24 months after radiotherapy, and comparisons between fractionation groups were done at 24 months post-radiotherapy.
Journal ArticleDOI
Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received
David E. Neal,Chris Metcalfe,Jenny L Donovan,J. Athene Lane,Michael Davis,Grace J. Young,Susan J Dutton,Eleanor I. Walsh,Richard M. Martin,Tim J Peters,Emma L Turner,Malcolm David Mason,Richard J. Bryant,Prasad Bollina,James W.F. Catto,Alan Doherty,David Gillatt,Vincent J. Gnanapragasam,Peter Holding,Owen Hughes,Roger Kockelbergh,Howard Kynaston,Jon Oxley,Alan Paul,Edgar Paez,Derek J. Rosario,Edward Rowe,John Staffurth,Doug G Altman,Freddie C. Hamdy,Andrew Doble,Philip Powell,Stephen Prescott,Derek Rosario,John Anderson,Jonathan Aning,Garett Durkan,Anthony Koupparis,Hing Y. Leung,Param Mariappan,Alan McNeill,Raj Persad,Hartwig Schwaibold,David N. Tulloch,Michael Wallace,Susan Bonnington,Lynne Bradshaw,Deborah Cooper,Emma Elliott,Phillipa Herbert,Joanne Howson,Amanda Jones,T Lennon,Norma Lyons,Hilary Moody,Claire Plumb,Tricia O'Sullivan,Elizabeth Salter,Pauline Thompson,Sarah Tidball,Jan Blaikie,Catherine Gray,Tonia Adam,Sarah Askew,Sharon Atkinson,Tim Baynes,Carole Brain,Viv Breen,Sarah Brunt,Sean Bryne,Jo Bythem,Jenny Clarke,Jenny Cloete,Susan Dark,Gill Davis,Rachael De La Rue,Jane Denizot,Elspeth Dewhurst,Anna Dimes,Nicola Dixon,Penny Ebbs,Ingrid Emmerson,Jill Ferguson,Ali Gadd,Lisa Geoghegan,Alison Grant,Collette Grant,Rosemary Godfrey,Louise Goodwin,Susie Hall,Liz Hart,Andrew Harvey,Chloe Hoult,Sarah Hawkins,Sharon Holling,Alastair Innes,Sue Kilner,Fiona Marshall,Louise Mellen,Andrea Moore,Sally Napier,Julie Needham,Kevin Pearse,Anna Pisa,Mark Rees,Ellie Richards,Lindsay Robson,Janet Roxburgh,Nikki Samuel,Irene Sharkey,Michael Slater,D. J. Smith,Pippa Taggart,Helen Taylor,Vicky Taylor,Ayesha Thomas,Briony Tomkies,Nicola Trewick,Claire Ward,Christy Walker,Ayesha Williams,C.R.J. Woodhouse,Elizabeth Wyber,Amit Bahl,Richard Benson,Mark Beresford,C.L. Ferguson,John Graham,Chris Herbert,Grahame Howard,Nicholas D. James,Peter Kirkbride,Alastair Law,Carmel Loughrey,Duncan McClaren,Helen Patterson,Ian Pedley,Trevor Roberts,Angus Robinson,Simon Russell,P. Symonds,Narottam Thanvi,Subramaniam Vasanthan,Paula Wilson,M.C. Robinson,Selina Bhattarai,Neeta Deshmukh,John Dormer,Malee Fernando,John R. Goepel,David J. Griffiths,Ken Grigor,Nick Mayer,Murali Varma,Anne Y. Warren,Helen Appleby,Dominic Ash,Dean Aston,Steven Bolton,Graham Chalmers,John Conway,Nick Early,Tony Geater,Lynda Goddall,Claire Heymann,Deborah Hicks,Liza Jones,Susan Lamb,Geoff Lambert,Gill Lawrence,Geraint Lewis,John Lilley,Aileen MacLeod,Pauline Massey,Alison McQueen,Rollo Moore,Lynda Penketh,Janet Potterton,Neil Roberts,Helen Showler,Pam Shuttleworth,Stephen Slade,Alasdair Steele,James Swinscoe,Marie Tiffany,John Townley,Jo Treeby,Michael Weston,Joyce Wilkinson,Lorraine Williams,Lucy Wills,O. Woodley,Sue Yarrow,Lucy Brindle,Linda Davies,D J Dedman,Elizabeth Down,Hanan Khazragui,Sian Noble,Hilary Taylor,Marta Tazewell,Julia Wade,Eleanor I Walsh,Susan Baker,Elizabeth Bellis-Sheldon,Chantal Bougard,Joanne Bowtell,Catherine Brewer,Chris Burton,Jennie Charlton,Nicholas Christoforou,Rebecca Clark,Susan Coull,Christine Croker,Rosemary Currer,Claire Daisey,Gill Delaney,Rose Donohue,Jane Drew,Rebecca Farmer,Susan Fry,Jean Haddow,Alex Hale,Susan Halpin,Belle Harris,Barbara Hattrick,Sharon Holmes,Helen Hunt,Vicky Jackson,Donna Johnson,Mandy Le Butt,Jo Leworthy,Tanya Liddiatt,Alex Martin,Jainee Mauree,Susan Moore,Gill Moulam,Jackie Mutch,Kathleen Parker,Christopher Pawsey,Michelle Purdie,Teresa Robson,Lynne Smith,Carole Stenton,Tom Steuart-Feilding,Beth Stott,Chris Sully,Caroline Sutton,Carol Torrington,Zoe Wilkins,Sharon Williams,Andrea Wilson,Ashleigh Weaver,Peter C. Albertsen,Jan Adolfsson,Michael Baum,Jon McFarlane,Colette Reid,Emma Turner,Anthony L. Zietman,Elizabeth M Hill,Siaw Yein Ng,Naomi J Williams,Jessica Toole,Charlotte F Davies,Laura J Hughes,Mari-Anne Rowlands,Lindsey Bell,Sean Harrison,Jainnee Mauree,Adrian Grant,Ian Roberts,Deborah Ashby,Richard A Cowan,Peter Fayers,Killian Mellon,James N'Dow,Tim O'Brien,Michael Sokhal,David P. Dearnaley,Fritz H. Schröder,Tracy E Roberts +281 more
TL;DR: Analyses according to treatment received showed increased rates of disease-related events and lower rates of patient-reported harms in menmanaged by AM compared with men managed by radical treatment, and stronger evidence of greater PCa mortality in the AM group.