H
Helen S. Mayberg
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 333
Citations - 50021
Helen S. Mayberg is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Deep brain stimulation & Major depressive disorder. The author has an hindex of 86, co-authored 288 publications receiving 44611 citations. Previous affiliations of Helen S. Mayberg include University of Nottingham & Harvard University.
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Journal ArticleDOI
Deep brain stimulation for treatment-resistant depression.
Helen S. Mayberg,Helen S. Mayberg,Andres M. Lozano,Valerie Voon,Heather E. McNeely,David A. Seminowicz,Clement Hamani,Jason M. Schwalb,Sidney H. Kennedy +8 more
TL;DR: It is suggested that disrupting focal pathological activity in limbic-cortical circuits using electrical stimulation of the subgenual cingulate white matter can effectively reverse symptoms in otherwise treatment-resistant depression.
Journal ArticleDOI
Toward discovery science of human brain function
Bharat B. Biswal,Maarten Mennes,Xi-Nian Zuo,Suril Gohel,Clare Kelly,Steve M. Smith,Christian F. Beckmann,Jonathan S. Adelstein,Randy L. Buckner,Stan Colcombe,Anne Marie Dogonowski,Monique Ernst,Damien A. Fair,Michelle Hampson,Matthew J. Hoptman,James S. Hyde,Vesa Kiviniemi,Rolf Kötter,Shi-Jiang Li,Ching Po Lin,Mark J. Lowe,Clare E. Mackay,David J. Madden,Kristoffer Hougaard Madsen,Daniel S. Margulies,Helen S. Mayberg,Katie L. McMahon,Christopher S. Monk,Stewart H. Mostofsky,Bonnie J. Nagel,James J. Pekar,Scott Peltier,Steven E. Petersen,Valentin Riedl,Serge A.R.B. Rombouts,Bart Rypma,Bradley L. Schlaggar,Sein Schmidt,Rachael D. Seidler,Greg J. Siegle,Christian Sorg,Gao Jun Teng,Juha Veijola,Arno Villringer,Martin Walter,Lihong Wang,Xu Chu Weng,Susan Whitfield-Gabrieli,Peter C. Williamson,Christian Windischberger,Yu-Feng Zang,Hong Ying Zhang,F. Xavier Castellanos,F. Xavier Castellanos,Michael P. Milham +54 more
TL;DR: The 1000 Functional Connectomes Project (Fcon_1000) as discussed by the authors is a large-scale collection of functional connectome data from 1,414 volunteers collected independently at 35 international centers.
Journal ArticleDOI
Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness
Helen S. Mayberg,Mario Liotti,Stephen K. Brannan,Scott M. McGinnis,Roderick K. Mahurin,Paul A Jerabek,J. Arturo Silva,Janet L. Tekell,C. C. Martin,Jack L. Lancaster,Peter T. Fox +10 more
TL;DR: Reciprocal changes involving subgenual cingulate and right prefrontal cortex occur with both transient and chronic changes in negative mood, suggesting that these regional interactions are obligatory and probably mediate the well-recognized relationships between mood and attention seen in both normal and pathological conditions.
Journal ArticleDOI
Limbic-cortical dysregulation: a proposed model of depression.
TL;DR: A working model of depression implicating failure of the coordinated interactions of a distributed network of limbic-cortical pathways is proposed to facilitate continued integration of clinical imaging findings with complementary neuroanatomical, neurochemical, and electrophysiological studies in the investigation of the pathogenesis of affective disorders.
Journal ArticleDOI
Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Andrew T. Drysdale,Logan Grosenick,Logan Grosenick,Jonathan Downar,Katharine Dunlop,Farrokh Mansouri,Yue Meng,Robert N. Fetcho,Benjamin D. Zebley,Desmond J. Oathes,Amit Etkin,Alan F. Schatzberg,Keith Sudheimer,Jennifer Keller,Helen S. Mayberg,Faith M. Gunning,George S. Alexopoulos,Michael D. Fox,Alvaro Pascual-Leone,Henning U. Voss,B. J. Casey,Marc J. Dubin,Conor Liston +22 more
TL;DR: It is shown here that patients with depression can be subdivided into four neurophysiological subtypes defined by distinct patterns of dysfunctional connectivity in limbic and frontostriatal networks, which may be useful for identifying the individuals who are most likely to benefit from targeted neurostimulation therapies.