H
Helen Steed
Researcher at University of Wolverhampton
Publications - 102
Citations - 3598
Helen Steed is an academic researcher from University of Wolverhampton. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 27, co-authored 78 publications receiving 2841 citations. Previous affiliations of Helen Steed include Cross Cancer Institute & New Cross Hospital.
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Journal ArticleDOI
Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics
TL;DR: Inulin-derived oligosaccharides and GOS are mildly laxative, but can result in flatulence and osmotic diarrhoea if taken in large amounts.
Journal ArticleDOI
Dose-Response Association of CD8(+) Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer
Ellen L. Goode,Matthew S. Block,Kimberly R. Kalli,Robert A. Vierkant,Wenqian Chen,Zachary C. Fogarty,Aleksandra Gentry-Maharaj,A. Toloczko,Alexander Hein,Aliecia L. Bouligny,Aliecia L. Bouligny,Allan Jensen,Ana Osorio,Andreas D. Hartkopf,Andy Ryan,Anita Chudecka-Głaz,Anthony M. Magliocco,Arndt Hartmann,Audrey Y. Jung,Bo Gao,Brenda Y. Hernandez,Brooke L. Fridley,Bryan M. McCauley,Catherine J. Kennedy,Catherine J. Kennedy,Chen Wang,Chloe Karpinskyj,Christiani Bisinoto de Sousa,Daniel Guimarães Tiezzi,David L. Wachter,Esther Herpel,Florin Andrei Taran,Francesmary Modugno,Gregg Nelson,Jan Lubinski,Janusz Menkiszak,Jennifer Alsop,Jenny Lester,Jesús García-Donas,Jill Nation,Jillian Hung,Jillian Hung,José Palacios,Joseph H. Rothstein,Joseph L. Kelley,Jurandyr Moreira de Andrade,Luis Robles-Díaz,Maria P. Intermaggio,Martin Widschwendter,Matthias W. Beckmann,Matthias Ruebner,Mercedes Jimenez-Linan,Naveena Singh,Oleg Oszurek,Paul R. Harnett,Peter F Rambau,Peter F Rambau,Peter Sinn,Philipp Wagner,Prafull Ghatage,Raghwa Sharma,Raghwa Sharma,Robert P. Edwards,Roberta B. Ness,Sandra Orsulic,Sara Y. Brucker,Sharon E. Johnatty,Teri A. Longacre,Ursula Eilber,Valerie McGuire,Weiva Sieh,Yanina Natanzon,Zheng Li,Zheng Li,Alice S. Whittemore,Anna deFazio,Anna deFazio,Annette Staebler,Beth Y. Karlan,Blake Gilks,David D.L. Bowtell,David D.L. Bowtell,David D.L. Bowtell,Estrid Høgdall,Francisco José Candido dos Reis,Helen Steed,Ian G. Campbell,Ian G. Campbell,Jacek Gronwald,Javier Benitez,Jennifer M Koziak,Jenny Chang-Claude,Jenny Chang-Claude,Kirsten B. Moysich,Linda E. Kelemen,Linda S. Cook,Marc T. Goodman,Maria J. Garcia,Peter A. Fasching,Peter A. Fasching,Stefan Kommoss,Suha Deen,Susanne K. Kjaer,Usha Menon,James D. Brenton,Paul D.P. Pharoah,Georgia Chenevix-Trench,David G. Huntsman,David G. Huntsman,Stacey J. Winham,Martin Köbel,Susan J. Ramus,Susan J. Ramus +112 more
TL;DR: This study demonstrates the histotype-specific nature of immune infiltration and provides definitive evidence for a dose-response relationship between CD8+ TILs and HGSOC survival and suggests that understanding factors that drive infiltration will be the key to unraveling outcome heterogeneity in this cancer.
Journal ArticleDOI
Clinical trial: the microbiological and immunological effects of synbiotic consumption - a randomized double-blind placebo-controlled study in active Crohn's disease.
Helen Steed,George T. Macfarlane,K. L. Blackett,Bahram Bahrami,Nigel Reynolds,Shaun V. Walsh,John H. Cummings,Sandra Macfarlane +7 more
TL;DR: Aliment Pharmacol Ther 2010; 32: 872–883.
Journal ArticleDOI
Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas
Michael S. Anglesio,Stefan Kommoss,Mary Catherine Tolcher,Blaise A. Clarke,Laura Galletta,Henry Porter,Sambasivarao Damaraju,Sian Fereday,Boris Winterhoff,Steve E. Kalloger,Janine Senz,Winnie Yang,Helen Steed,Ghassan Allo,Sarah E. Ferguson,Patricia Shaw,Attila Teoman,Joaquin J. Garcia,John K. Schoolmeester,Jamie N. Bakkum-Gamez,Anna V. Tinker,David D.L. Bowtell,David D.L. Bowtell,David G. Huntsman,C. Blake Gilks,Jessica N. McAlpine +25 more
TL;DR: The stratification of MCs for the testing of new treatments, with HER2‐targeted therapy as a viable option for HER2+ advanced or recurrent disease is supported.
Journal ArticleDOI
Oesophageal bacterial biofilm changes in gastro‐oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality?
K. L. Blackett,S. S. Siddhi,S. Cleary,Helen Steed,Michael H Miller,Sandra Macfarlane,George T. Macfarlane,John F. Dillon +7 more
TL;DR: There is an oesophageal biofilm, which changes in disease, but its role in aetiopathogenesis remains unclear.