H
Helena C. Kraemer
Researcher at Stanford University
Publications - 565
Citations - 70397
Helena C. Kraemer is an academic researcher from Stanford University. The author has contributed to research in topics: Randomized controlled trial & Population. The author has an hindex of 132, co-authored 562 publications receiving 65755 citations. Previous affiliations of Helena C. Kraemer include VA Palo Alto Healthcare System & University of Nairobi.
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Journal ArticleDOI
Mediators and Moderators of Treatment Effects in Randomized Clinical Trials
TL;DR: An analytic framework is described to identify and distinguish between moderators and mediators in RCTs when outcomes are measured dimensionally and it is recommended that R CTs routinely include and report such analyses.
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The MATRICS Consensus Cognitive Battery, Part 1: Test Selection, Reliability, and Validity
Keith H. Nuechterlein,Michael F. Green,Robert S. Kern,Lyle E. Baade,M Deanna,Jonathan D. Cohen,Susan M. Essock,Wayne S. Fenton,Frederick J. Frese,James M. Gold,Terry E. Goldberg,Robert K. Heaton,Richard S.E. Keefe,Helena C. Kraemer,Raquelle I. Mesholam-Gately,Larry J. Seidman,Ellen Stover,Daniel R. Weinberger,Alexander S. Young,Steven Zalcman,Stephen R. Marder +20 more
TL;DR: The MATRICS Consensus Cognitive Battery is expected to be the standard tool for assessing cognitive change in clinical trials of cognition-enhancing drugs for schizophrenia and may also aid evaluation of cognitive remediation strategies.
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How Do Risk Factors Work Together? Mediators, Moderators, and Independent, Overlapping, and Proxy Risk Factors
TL;DR: Classifying putative risk factors into these qualitatively different types can help identify high-risk individuals in need of preventive interventions and can help inform the content of such interventions.
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The role and interpretation of pilot studies in clinical research
TL;DR: The roles and limitations of pilot studies are described here using a clinical trial as an example to evaluate the feasibility of recruitment, randomization, retention, assessment procedures, new methods, and implementation of the novel intervention.
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Coming to Terms With the Terms of Risk
Helena C. Kraemer,Alan E. Kazdin,David R. Offord,Ronald C. Kessler,Peter S. Jensen,David J. Kupfer +5 more
TL;DR: This work defines risk and a risk factor (protective factor) and their potency, set out the conceptual basis of the methods by which risk factors are identified and potency demonstrated, and proposes criteria for establishing the status of a risk factors as a fixed or variable marker or a causal risk factor.