Helmy Eltoukhy

TL;DR: This article provides a basic introduction to CMOS image-sensor technology, design and performance limits and presents recent developments and future research directions enabled by pixel-level processing, which promise to further improveCMOS image sensor performance and broaden their applicability beyond current markets.

TL;DR: The analytic and clinical validation of the gene panel are reported and near-perfect analytic specificity enables complete coverage of many genes without the false positives typically seen with traditional sequencing assays at mutant allele frequencies or fractions below 5%.

TL;DR: High concordance with orthogonal clinical plasma- and tissue-based genotyping methods supports the clinical accuracy of digital sequencing across all four types of targetable genomic alterations.

TL;DR: Together, these retrospective analyses of a large cfDNA sequencing data set reveal subclonal structures and emerging resistance in advanced solid tumors.

TL;DR: In this paper, the authors describe a bioluminescence detection lab-on-chip consisting of a fiber-optic faceplate with immobilized luminescent reporters/probes that is directly coupled to an optical detection and processing CMOS system on-chip (SoC).