H
Hend Mohamed Abdel-Bar
Researcher at University of Sadat City
Publications - 12
Citations - 171
Hend Mohamed Abdel-Bar is an academic researcher from University of Sadat City. The author has contributed to research in topics: Virtual screening & Druggability. The author has an hindex of 4, co-authored 12 publications receiving 37 citations. Previous affiliations of Hend Mohamed Abdel-Bar include King's College London.
Papers
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Journal ArticleDOI
Investigating the Internalization and COVID-19 Antiviral Computational Analysis of Optimized Nanoscale Zinc Oxide
Mohamed Hamdi,Hend Mohamed Abdel-Bar,Enas Elmowafy,Ahmed El-Khouly,Ahmed El-Khouly,Mai Mansour,Gehanne A.S. Awad +6 more
TL;DR: In this article, a nanoscale zinc oxide (ZnO) nanoparticles (NPs) were fabricated and relevant aspects related to the formulation such as optimization, structure, purity, and morphology were elucidated.
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An "eat me" combinatory nano-formulation for systemic immunotherapy of solid tumors.
Hend Mohamed Abdel-Bar,Hend Mohamed Abdel-Bar,Adam A. Walters,Yau Lim,Nadia Rouatbi,Yue Qin,Fatemeh Gheidari,Shunping Han,Rihab Osman,Julie Tzu-Wen Wang,Khuloud T. Al-Jamal +10 more
TL;DR: In this article, a stable nucleic acid-lipid particles (SNALPs) formulation for the simultaneous delivery of ICD inducing drug (Dox) with small interfering RNA (siRNA) knocking down CD47 (siCD47), the dominant 'don't eat me' marker, was presented.
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Synchronizing In Silico, In Vitro, and In Vivo Studies for the Successful Nose to Brain Delivery of an Anticancer Molecule.
Shaymaa A. Abd-algaleel,Abdelkader A. Metwally,Abdelkader A. Metwally,Hend Mohamed Abdel-Bar,Dina H. Kassem,Rania M. Hathout +5 more
TL;DR: The results proved the power of combined in silico tools in predicting members with the highest sesamol payload suitable for delivering a sufficient dose to the brain and showed how different formulations, having different compositions and characteristics, could affect the cytotoxic and targeting ability.
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An integrated vitamin E-coated polymer hybrid nanoplatform: A lucrative option for an enhanced in vitro macrophage retention for an anti-hepatitis B therapeutic prospect.
TL;DR: The presented formulation displayed promising traits, enhancing the cellular retention in J774 macrophages cells, and in vivo and antiviral activity futuristic studies would help in the potential application of the ELPH in hepatitis B control.
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Folate-chitosan nanoparticles triggered insulin cellular uptake and improved in vivo hypoglycemic activity.
TL;DR: The aim of this study was to prove a prolonged control of glucose levels, in rats, by the oral use of insulinfolate-chitosan nanoparticles (FA-CS NPs), which was able to enhance the stability of insulin in presence of GIT enzymes.