H
Henning Flechtner
Researcher at Otto-von-Guericke University Magdeburg
Publications - 40
Citations - 14651
Henning Flechtner is an academic researcher from Otto-von-Guericke University Magdeburg. The author has contributed to research in topics: Quality of life & Cancer. The author has an hindex of 19, co-authored 37 publications receiving 12848 citations. Previous affiliations of Henning Flechtner include University of Cologne.
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Journal ArticleDOI
The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
Neil K. Aaronson,Sam H Ahmedzai,Bengt Bergman,Monika Bullinger,Ann Cull,Nicole Duez,Antonio Filiberti,Henning Flechtner,Stewart B. Fleishman,Johanna C. J. M. de Haes,Stein Kaasa,M. Klee,David Osoba,Darius Razavi,Peter B. Rofe,Simon Schraub,Kommer C. A. Sneeuw,Marianne Sullivan,Fumikazu Takeda +18 more
TL;DR: The reliability and validity of the EORTC QLQ-C30 questionnaire were highly consistent across the three language-cultural groups studied: patients from English-speaking countries, Northern Europe, and Southern Europe.
Journal ArticleDOI
Beyond the Development of Health-Related Quality-of-Life (HRQOL) Measures: A Checklist for Evaluating HRQOL Outcomes in Cancer Clinical Trials--Does HRQOL Evaluation in Prostate Cancer Research Inform Clinical Decision Making?
Fabio Efficace,Andrew Bottomley,David Osoba,Carolyn C. Gotay,Henning Flechtner,Sven D’Haese,Alfredo Zurlo +6 more
TL;DR: It was found that HRQOL is a valuable source of information in RCTs of treatment in metastatic prostate cancer and a minimum set of criteria for assessing the reported outcomes in cancer clinical trials is necessary to make informed decisions in clinical practice.
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Patient Self-Reports of Symptoms and Clinician Ratings as Predictors of Overall Cancer Survival
C. Quinten,J. Maringwa,Carolyn C. Gotay,Francesca Martinelli,Corneel Coens,Bryce B. Reeve,Henning Flechtner,Eva Greimel,Madeleine King,David Osoba,Charles S. Cleeland,Jolie Ringash,Joseph Schmucker-Von Koch,Martin J.B. Taphoorn,Joachim Weis,Andrew Bottomley +15 more
TL;DR: Patients provide a subjective measure of symptom severity that complements clinician scoring in predicting overall survival, and Cox models of overall survival that considered both patient and clinician scores gained more predictive accuracy.
The EORTC core quality of life questionnaire: interim results of an international field study
Neil K. Aaronson,Sam H Ahmedzai,Monika Bullinger,D. Crabeels,J. Estape,A Filiberti,Henning Flechtner,Ulrich Frick,Christoph Hürny,Stein Kaasa,M. Klee,M. Mastilica,David Osoba,P. Fausler,Darius Razavi,Simon Schraub,Marianne Sullivan,F Takeda +17 more
TL;DR: The juice is homogenized by applying vigorous and repeated shearing action to cause extensive damage to the fruit cells and thereby increase the consistency of the juice.
Journal ArticleDOI
A global analysis of multitrial data investigating quality of life and symptoms as prognostic factors for survival in different tumor sites
C. Quinten,Francesca Martinelli,Corneel Coens,Mirjam A. G. Sprangers,Jolie Ringash,Carolyn C. Gotay,Kristin Bjordal,Eva Greimel,Bryce B. Reeve,J. Maringwa,Divine E. Ediebah,Efstathios Zikos,Madeleine King,David Osoba,Martin J B Taphoorn,Henning Flechtner,Joseph Schmucker-Von Koch,Joachim Weis,Andrew Bottomley +18 more
TL;DR: The objective of this study was to examine the prognostic value of baseline health‐related quality of life (HRQOL) for survival with regard to different cancer sites using 1 standardized and validated patient self‐assessment tool.