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Henriette N. Buttenschøn
Researcher at Aarhus University
Publications - 59
Citations - 3936
Henriette N. Buttenschøn is an academic researcher from Aarhus University. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 25, co-authored 57 publications receiving 3022 citations. Previous affiliations of Henriette N. Buttenschøn include Aarhus University Hospital & Lundbeck.
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Journal ArticleDOI
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray,Stephan Ripke,Stephan Ripke,Stephan Ripke,Manuel Mattheisen,Maciej Trzaskowski,Enda M. Byrne,Abdel Abdellaoui,Mark Adams,Esben Agerbo,Esben Agerbo,Tracy Air,Till M.F. Andlauer,Silviu Alin Bacanu,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Aartjan F.T. Beekman,Tim B. Bigdeli,Elisabeth B. Binder,Elisabeth B. Binder,Douglas Blackwood,Julien Bryois,Henriette N. Buttenschøn,Henriette N. Buttenschøn,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,Na Cai,Na Cai,Enrique Castelao,Jane H. Christensen,Jane H. Christensen,Toni-Kim Clarke,Jonathan I.R. Coleman,Lucía Colodro-Conde,Baptiste Couvy-Duchesne,Nicholas John Craddock,Gregory E. Crawford,Cheynna A. Crowley,Hassan S. Dashti,Hassan S. Dashti,Gail Davies,Ian J. Deary,Franziska Degenhardt,Eske M. Derks,Nese Direk,Nese Direk,Conor V. Dolan,Erin C. Dunn,Erin C. Dunn,Thalia C. Eley,Nicholas Eriksson,Valentina Escott-Price,Farnush Hassan Farhadi Kiadeh,Hilary K. Finucane,Hilary K. Finucane,Andreas J. Forstner,Josef Frank,Helena Gaspar,Michael Gill,Paola Giusti-Rodríguez,Fernando S. Goes,Scott D. Gordon,Jakob Grove,Lynsey S. Hall,Lynsey S. Hall,Eilis Hannon,Christine Søholm Hansen,Christine Søholm Hansen,Thomas Hansen,Thomas Hansen,Stefan Herms,Stefan Herms,Ian B. Hickie,Per Hoffmann,Per Hoffmann,Georg Homuth,Carsten Horn,Jouke-Jan Hottenga,David M. Hougaard,David M. Hougaard,Ming Hu,Craig L. Hyde,Marcus Ising,Rick Jansen,Fulai Jin,Eric Jorgenson,James A. Knowles,Isaac S. Kohane,Isaac S. Kohane,Isaac S. Kohane,Julia Kraft,Warren W. Kretzschmar,Jesper Krogh,Zoltán Kutalik,Zoltán Kutalik,Jacqueline M. Lane,Jacqueline M. Lane,Yihan Li,Yun Li,Penelope A. Lind,Xiaoxiao Liu,Leina Lu,Donald J. MacIntyre,Dean F. MacKinnon,Robert Maier,Wolfgang Maier,Jonathan Marchini,Hamdi Mbarek,Patrick J. McGrath,Peter McGuffin,Sarah E. Medland,Divya Mehta,Divya Mehta,Christel M. Middeldorp,Christel M. Middeldorp,Evelin Mihailov,Yuri Milaneschi,Lili Milani,Jonathan Mill,Francis M. Mondimore,Grant W. Montgomery,Sara Mostafavi,Niamh Mullins,Matthias Nauck,Bernard Ng,Michel G. Nivard,Dale R. Nyholt,Paul F. O'Reilly,Hogni Oskarsson,Michael John Owen,Jodie N. Painter,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Roseann E. Peterson,Erik Pettersson,Wouter J. Peyrot,Giorgio Pistis,Danielle Posthuma,Shaun Purcell,Jorge A. Quiroz,Per Qvist,Per Qvist,John P. Rice,Brien P. Riley,Margarita Rivera,Margarita Rivera,Saira Saeed Mirza,Richa Saxena,Richa Saxena,Robert A. Schoevers,Eva C. Schulte,Ling Shen,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Grant Sinnamon,Johannes H. Smit,Daniel J. Smith,Hreinn Stefansson,Stacy Steinberg,Craig A. Stockmeier,Fabian Streit,Jana Strohmaier,Katherine E. Tansey,Henning Teismann,Alexander Teumer,Wesley K. Thompson,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Chao Tian,Matthew Traylor,Jens Treutlein,Vassily Trubetskoy,André G. Uitterlinden,Daniel Umbricht,Sandra Van der Auwera,Albert M. van Hemert,Alexander Viktorin,Peter M. Visscher,Yunpeng Wang,Yunpeng Wang,Yunpeng Wang,Bradley T. Webb,Shantel Weinsheimer,Shantel Weinsheimer,Jürgen Wellmann,Gonneke Willemsen,Stephanie H. Witt,Yang Wu,Hualin S. Xi,Jian Yang,Futao Zhang,Volker Arolt,Bernhard T. Baune,Klaus Berger,Dorret I. Boomsma,Sven Cichon,Udo Dannlowski,E. C.J. De Geus,J. Raymond DePaulo,Enrico Domenici,Katharina Domschke,Tõnu Esko,Tõnu Esko,Hans J. Grabe,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,David A. Hinds,Kenneth S. Kendler,Stefan Kloiber,Stefan Kloiber,Stefan Kloiber,Glyn Lewis,Qingqin S. Li,Susanne Lucae,Pamela F.A. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Andres Metspalu,Ole Mors,Ole Mors,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Sara A. Paciga,Nancy L. Pedersen,Brenda W.J.H. Penninx,Roy H. Perlis,David J. Porteous,James B. Potash,Martin Preisig,Marcella Rietschel,Catherine Schaefer,Thomas G. Schulze,Jordan W. Smoller,Jordan W. Smoller,Kari Stefansson,Kari Stefansson,Henning Tiemeier,Rudolf Uher,Henry Völzke,Myrna M. Weissman,Myrna M. Weissman,Thomas Werge,Thomas Werge,Thomas Werge,Ashley R. Winslow,Ashley R. Winslow,Cathryn M. Lewis,Douglas F. Levinson,Gerome Breen,Anders D. Børglum,Anders D. Børglum,Patrick F. Sullivan,Patrick F. Sullivan +262 more
TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Journal ArticleDOI
Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression
Ole Köhler-Forsberg,Ole Köhler-Forsberg,Henriette N. Buttenschøn,Katherine E. Tansey,Wolfgang Maier,Joanna Hauser,Mojca Z. Dernovsek,Neven Henigsberg,Daniel Souery,Anne Farmer,Marcella Rietschel,Peter McGuffin,Katherine J. Aitchison,Rudolf Uher,Ole Mors +14 more
TL;DR: The results support the sickness syndrome theory suggesting that chronic low-grade inflammation may be associated with a subtype of depression and clinical studies should investigate symptom-specific and/or gender-specific treatment guided by peripheral inflammatory markers.
Journal ArticleDOI
Genome-wide association for major depression through age at onset stratification: Major depressive disorder working group of the Psychiatric Genomics Consortium
Robert Power,Katherine E. Tansey,Henriette N. Buttenschøn,Sarah Cohen-Woods,Tim B. Bigdeli,Lynsey S. Hall,Zoltán Kutalik,S. Hong Lee,S. Hong Lee,Stephan Ripke,Stephan Ripke,Stephan Ripke,Stacy Steinberg,Alexander Teumer,Alexander Viktorin,Naomi R. Wray,Volker Arolt,Bernard T. Baune,Dorret I. Boomsma,Anders D. Børglum,Enda M. Byrne,Enrique Castelao,Nicholas John Craddock,Ian W. Craig,Udo Dannlowski,Udo Dannlowski,Ian J. Deary,Franziska Degenhardt,Andreas J. Forstner,Scott D. Gordon,Hans J. Grabe,Jakob Grove,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,Lynne J. Hocking,Georg Homuth,Jouke J. Hottenga,Stefan Kloiber,Jesper Krogh,Mikael Landén,Mikael Landén,Maren Lang,Douglas F. Levinson,Paul Lichtenstein,Susanne Lucae,Donald J. MacIntyre,Pamela A. F. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Christel M. Middeldorp,Yuri Milaneschi,Grant W. Montgomery,Ole Mors,Ole Mors,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Dale R. Nyholt,Hogni Oskarsson,Michael John Owen,Sandosh Padmanabhan,Brenda W.J.H. Penninx,Michele L. Pergadia,David J. Porteous,James B. Potash,Martin Preisig,Margarita Rivera,Margarita Rivera,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Johannes H. Smit,Blair H. Smith,Hreinn Stefansson,Kari Stefansson,Jana Strohmaier,Patrick F. Sullivan,Patrick F. Sullivan,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Sandra Van der Auwera,Myrna M. Weissman,Gerome Breen,Cathryn M. Lewis +84 more
TL;DR: It is demonstrated that using additional phenotype data previously collected by genetic studies to tackle phenotypic heterogeneity in MDD can successfully lead to the discovery of genetic risk factor despite reduced sample size.
Journal ArticleDOI
The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion
Camilla Gustafsen,Mads Kjolby,Mads Kjolby,Mette Nyegaard,Manuel Mattheisen,Jesper Lundhede,Henriette N. Buttenschøn,Ole Mors,Ole Mors,Jacob F. Bentzon,Peder Madsen,Anders Nykjaer,Simon Glerup +12 more
TL;DR: Sortilin is identified, encoded by the hypercholesterolemia-risk gene SORT1, as a high-affinity sorting receptor for PCSK9, establishing sortilin as a critical regulator ofPCSK9 activity.
Journal ArticleDOI
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Stephanie H. Witt,Fabian Streit,Martin Jungkunz,Josef Frank,Swapnil Awasthi,Céline S. Reinbold,Jens Treutlein,Franziska Degenhardt,Andreas J. Forstner,Stefanie Heilmann-Heimbach,Lydie Dietl,C. E. Schwarze,Darja Schendel,Jana Strohmaier,Abdel Abdellaoui,Rolf Adolfsson,Tracy Air,Huda Akil,Martin Alda,Ney Alliey-Rodriguez,Ole A. Andreassen,Ole A. Andreassen,Gulja Babadjanova,N Bass,Michael Bauer,Bernhard T. Baune,Franck Bellivier,Sarah E. Bergen,Andrew Bethell,Joanna M. Biernacka,Douglas Blackwood,Marco P. Boks,Dorret I. Boomsma,Anders D. Børglum,Anders D. Børglum,Margitta Borrmann-Hassenbach,Patrick J. Brennan,Monika Budde,Monika Budde,Henriette N. Buttenschøn,Enda M. Byrne,Pablo Cervantes,Toni-Kim Clarke,Nicholas John Craddock,Cristiana Cruceanu,David Curtis,David Curtis,Piotr M. Czerski,Udo Dannlowski,Tony Davis,E.J.C. de Geus,A. Di Florio,Srdjan Djurovic,Srdjan Djurovic,Enrico Domenici,Howard J. Edenberg,Bruno Etain,Sascha B. Fischer,Liz Forty,Christine Fraser,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Katrin Gade,Katrin Gade,Elliot S. Gershon,Ina Giegling,Scott D. Gordon,Katherine Gordon-Smith,Hans-Jörgen Grabe,Elaine K. Green,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Jose Guzman-Parra,Lisa Hall,Lisa Hall,Marian L. Hamshere,Joanna Hauser,Martin Hautzinger,Urs Heilbronner,Stefan Herms,Stefan Herms,Shashi Hitturlingappa,Peter Hoffmann,Peter Hoffmann,Peter Holmans,Jouke-Jan Hottenga,Stéphane Jamain,Stéphane Jamain,Ian Jones,Lisa Jones,Anders Juréus,René S. Kahn,Jutta Kammerer-Ciernioch,G. Kirov,Sarah Kittel-Schneider,Stefan Kloiber,Stefan Kloiber,Stefan Kloiber,Sarah Knott,Manolis Kogevinas,Mikael Landén,Mikael Landén,Markus Leber,Marion Leboyer,Qingqin S. Li,Jolanta Lissowska,Susanne Lucae,Nicholas G. Martin,Nicholas G. Martin,Fermin Mayoral-Cleries,Susan L. McElroy,Andrew M. McIntosh,James D. McKay,Andrew McQuillin,S. E. Medland,Christel M. Middeldorp,Y. Milaneschi,Philip B. Mitchell,Philip B. Mitchell,Grant W. Montgomery,Gunnar Morken,Ole Mors,Ole Mors,Thomas W. Mühleisen,Thomas W. Mühleisen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Richard M. Myers,Caroline M. Nievergelt,John I. Nurnberger,Michael Conlon O'Donovan,Loes M. Olde Loohuis,Roel A. Ophoff,Lilijana Oruc,M. J. Owen,Sara A. Paciga,B.W.J.H. Penninx,Amy Perry,Andrea Pfennig,James B. Potash,Martin Preisig,Andreas Reif,Fabio Rivas,Guy A. Rouleau,Guy A. Rouleau,Peter R. Schofield,Peter R. Schofield,Thomas G. Schulze,Markus Schwarz,Laura J. Scott,Grant C.B. Sinnamon,Eli A. Stahl,Eli A. Stahl,John Strauss,Gustavo Turecki,S Van der Auwera,Helmut Vedder,John B. Vincent,Gonneke Willemsen,Christian Witt,Naomi R. Wray,Hualin S. Xi,André Tadić,N. Dahmen,Björn H. Schott,Björn H. Schott,Sven Cichon,M. M. Nöthen,Stephan Ripke,Stephan Ripke,Stephan Ripke,Arian Mobascher,Dan Rujescu,Klaus Lieb,Stefan Roepke,Christian Schmahl,Martin Bohus,Marcella Rietschel +178 more
TL;DR: This study is the first to demonstrate that BOR overlaps with BIP, MDD and SCZ on the genetic level, and whether this is confined to transdiagnostic clinical symptoms should be examined in future studies.