H
Hideharu Tatebayashi
Researcher at Northwestern University
Publications - 6
Citations - 367
Hideharu Tatebayashi is an academic researcher from Northwestern University. The author has contributed to research in topics: Sodium channel & GABAA receptor. The author has an hindex of 5, co-authored 6 publications receiving 362 citations.
Papers
More filters
Journal Article
Ion channels as targets for insecticides
TL;DR: The method with which the percentage of sodium channel population that needs to be modified to cause repetitive after-discharges can be measured accurately is developed and is applicable to other neuroactive drugs that act through the threshold phenomenon.
Journal ArticleDOI
Interactions of tetramethrin, fenvalerate and DDT at the sodium channel in rat dorsal root ganglion neurons
TL;DR: Type I and type II pyrethroids and dichlorodiphenyltrichloroethane (DDT) are known to modulate the sodium channel to cause the hyperexcitatory symptoms of poisoning in animals, but a question is raised as to whether these insecticides bind to the same site in the Sodium channel.
Journal ArticleDOI
Sodium channels and GABAA receptor-channel complex as targets of environmental toxicants
Toshio Narahashi,Donald B. Carter,J. M. Frey,Kenneth S. Ginsburg,Beverly J. hamilton,Keiichi Nagata,Mary Louise Roy,Jin-Ho Song,Hideharu Tatebayashi +8 more
TL;DR: The selective pyrethroid toxicity between mammals and insects can be quantitatively explained on the basis of the differences in 5 factors, i.e. the intrinsic sodium channel sensitivity, the sodium channel modification due to temperature difference, the reversibility of sodium channel, the detoxication of pyrethroids, and body size.
Journal ArticleDOI
Alcohol modulation of single GABA(A) receptor-channel kinetics.
TL;DR: Modulation of single-channel kinetics of GABAA receptor currents was studied with rat dorsal root ganglion neurons using the excised outside-out patch clamp technique and changes in channel kinetics account for the increase in whole-cell current amplitude caused by ethanol and n-Octanol.