H
Hirohiko Nakae
Researcher at Tokai University
Publications - 8
Citations - 214
Hirohiko Nakae is an academic researcher from Tokai University. The author has contributed to research in topics: Placebo-controlled study & Brunner's glands. The author has an hindex of 5, co-authored 8 publications receiving 154 citations.
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Journal ArticleDOI
Alteration in the gastric microbiota and its restoration by probiotics in patients with functional dyspepsia.
Muneki Igarashi,Hirohiko Nakae,Takashi Matsuoka,Shunsuke Takahashi,Takayoshi Hisada,Junko Tomita,Yasuhiro Koga +6 more
TL;DR: Altered in the GF microbiota was found in patients with functional dyspepsia compared with HC volunteers, and Probiotics appear effective in the treatment of FD through the normalisation of gastric microbiota.
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Gastric microbiota in the functional dyspepsia patients treated with probiotic yogurt
TL;DR: Significant dysbiosis was found in the GF microbiota of patients with FD and considered to be involved in the pathogenesis and may be used as a biomarker of the efficacy of the treatment of FD.
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Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
Takayoshi Suzuki,Aya Masui,Jun Nakamura,Hirokazu Shiozawa,Jun Aoki,Hirohiko Nakae,Shingo Tsuda,Jin Imai,Ozawa Hideki,Masashi Matsushima,Tetsuya Mine,Akira Tamura,Toshihiro Ohtsu,Yukio Asami,Atsushi Takagi +14 more
TL;DR: It is found that LG may be useful in reducing aspirin-induced small bowel injuries and in mitigating gastrointestinal symptoms and the FSSG and GSRS scores were significantly improved in the LG group but not in the placebo group.
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Prediction of steroid demand in the treatment of patients with ulcerative colitis by immunohistochemical analysis of the mucosal microenvironment and immune checkpoint: role of macrophages and regulatory markers in disease severity.
Shingo Tsuda,Joaquim Carreras,Yara Yukie Kikuti,Hirohiko Nakae,Makiko Dekiden-Monma,Jin Imai,Kota Tsuruya,Jun Nakamura,Yoko Tsukune,Tetsufumi Uchida,Masashi Matsushima,Giovanna Roncador,Takayoshi Suzuki,Naoya Nakamura,Tetsuya Mine +14 more
TL;DR: In this article, the mucosal immune microenvironment and immune checkpoint of Ulcerative colitis (UC) were characterized by immunohistochemistry with correlation to prognosis: requirement of second-line steroid-therapy within the 2-years after diagnosis (SR).
Journal ArticleDOI
Usefulness of Acoustic Monitoring of Respiratory Rate in Patients Undergoing Endoscopic Submucosal Dissection
Takayoshi Suzuki,Shingo Tsuda,Hirohiko Nakae,Jin Imai,Kana Sawamoto,Maiko Kijima,Yoko Tsukune,Tetsufumi Uchida,Muneki Igarashi,Jun Koike,Masashi Matsushima,Toshiyasu Suzuki,Tetsuya Mine +12 more
TL;DR: The difference in RR before treatment between patients with and without respiratory suppression was subtle and it is suggested that acoustic RR monitoring should be considered in patients undergoing ESD under sedation to prevent serious respiratory complications.