Hisayuki Matsuo

TL;DR: Cloning and sequence analysis of cDNA for the Electrophorus electricus electroplax sodium channel indicate that this protein exhibits four repeated homology units, which are presumably oriented in a pseudosymmetric fashion across the membrane.

TL;DR: The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photo-receptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, followed by a region that is similar to the cyclo-GMP-binding domains of cyclicGMP-dependent protein kinase.

TL;DR: The amino-acid sequence deduced from the cDNA sequence reveals that the Jk RS-binding protein has a sequence similar to the 40-residue motif of integrases of phages, bacteria and yeast, indicating that this protein could be involved in V-(D)-Jrecombination as a recombinase.

TL;DR: The pharmacokinetics ofα-human atrial natriuretic polypeptide (α-hANP) in healthy subjects, using a two-compartment open model following bolus intravenous injection, were analysed.

TL;DR: Results suggest that plasma AM levels are increased in heart failure in proportion to the severity of heart failure and that cardiac production and secretion of AM is increased inHeart failure rats, and the lung may be another site for increased production of AM in heart failures.