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Ho-Youn Kim

Researcher at Catholic University of Korea

Publications -  279
Citations -  12147

Ho-Youn Kim is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Arthritis & Rheumatoid arthritis. The author has an hindex of 57, co-authored 279 publications receiving 11053 citations. Previous affiliations of Ho-Youn Kim include The Catholic University of America & St Mary's Hospital.

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IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways

TL;DR: IL-17 appears to be a stronger inducer of IL-6 and IL-8 than IL-15, and even exerted activation comparable to that ofIL-1β in RA FLS, and provide grounds for targeting IL-17-associated pathways in therapeutic modulation of arthritis inflammation.
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STAT3 and NF-κB Signal Pathway Is Required for IL-23-Mediated IL-17 Production in Spontaneous Arthritis Animal Model IL-1 Receptor Antagonist-Deficient Mice

TL;DR: The data suggest that IL-23 seems to be a central proinflammatory cytokine in the pathogenesis of this IL-1Ra−/− model of spontaneous arthritis, and its intracellular signaling pathway could be useful therapeutic targets in the treatment of autoimmune arthritis.
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The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.

TL;DR: It is found that TLRs are increased in OA cartilage lesions after treatment with TLR ligands led to phosphorylation of 3 MAPKs and activation of NF-kappaB.
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Correction: Corrigendum: PTEN ameliorates autoimmune arthritis through down-regulating STAT3 activation with reciprocal balance of Th17 and Tregs

TL;DR: This corrects the article DOI: 10.1038/srep34617 to indicate that the author of the paper is a doctor of medicine rather than a scientist, as previously reported.