H
Hoi Wah Tsoi
Researcher at University of Hong Kong
Publications - 22
Citations - 10011
Hoi Wah Tsoi is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Coronavirus & Genome. The author has an hindex of 16, co-authored 19 publications receiving 8097 citations. Previous affiliations of Hoi Wah Tsoi include Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Journal ArticleDOI
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.
Jasper Fuk-Woo Chan,Shuofeng Yuan,Kin-Hang Kok,Kelvin K. W. To,Kelvin K. W. To,Hin Chu,Jin Yang,Fanfan Xing,Jieling Liu,Cyril C. Y. Yip,Rosana W.S. Poon,Hoi Wah Tsoi,Simon Kam Fai Lo,Kwok-Hung Chan,Vincent Kwok-Man Poon,Wan Mui Chan,Jonathan Daniel Ip,Jian Piao Cai,Vincent C.C. Cheng,Honglin Chen,Honglin Chen,Christopher K.M. Hui,Kwok-Yung Yuen +22 more
TL;DR: The findings are consistent with person-to-person transmission of this novel coronavirus in hospital and family settings, and the reports of infected travellers in other geographical regions.
Journal ArticleDOI
Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility.
Jasper Fuk-Woo Chan,Jasper Fuk-Woo Chan,Jasper Fuk-Woo Chan,Anna Jinxia Zhang,Shuofeng Yuan,Vincent Kwok-Man Poon,Chris Chung-Sing Chan,Andrew Chak-Yiu Lee,Wan Mui Chan,Zhimeng Fan,Hoi Wah Tsoi,Lei Wen,Ronghui Liang,Jianli Cao,Yanxia Chen,Kaiming Tang,Cuiting Luo,Jian Piao Cai,Kin-Hang Kok,Hin Chu,Kwok-Hung Chan,Siddharth Sridhar,Siddharth Sridhar,Siddharth Sridhar,Zhiwei Chen,Honglin Chen,Kelvin K. W. To,Kelvin K. W. To,Kelvin K. W. To,Kwok-Yung Yuen,Kwok-Yung Yuen,Kwok-Yung Yuen +31 more
TL;DR: Besides satisfying the Koch’s postulates, this readily available hamster model is an important tool for studying transmission, pathogenesis, treatment, and vaccination against SARS-CoV-2.
Journal ArticleDOI
Molecular diversity of coronaviruses in bats.
Patrick C. Y. Woo,Susanna K. P. Lau,Kenneth S. M. Li,Rosana W.S. Poon,Beatrice H.L. Wong,Hoi Wah Tsoi,Bethanie C.K. Yip,Yi Huang,Kwok-Hung Chan,Kwok-Yung Yuen +9 more
TL;DR: Phylogenetic analysis of RNA-dependent-RNA-polymerase (pol) and helicase genes revealed six novel coronaviruses from six different bat species, in addition to the two previously described coronavirus in bats.
Journal ArticleDOI
Clinical and molecular epidemiological features of coronavirus HKU1-associated community-acquired pneumonia.
Patrick C. Y. Woo,Susanna K. P. Lau,Hoi Wah Tsoi,Yi Huang,Rosana W.S. Poon,Chung-Ming Chu,Rodney A. Lee,Wei-Kwang Luk,Gilman K. M. Wong,Beatrice H.L. Wong,Vincent C.C. Cheng,Bone S.F. Tang,Alan K.L. Wu,Raymond W. H. Yung,Honglin Chen,Yi Guan,Kwok-Hung Chan,Kwok-Yung Yuen +17 more
TL;DR: CoV-HKU1 accounts for 2.4% of community-acquired pneumonia, with 2 genotypes in the study population, without performance of diagnostic tests, the illness was clinically indistinguishable from other community- Acquired pneumonia illnesses.
Journal ArticleDOI
Comparative analysis of 22 coronavirus HKU1 genomes reveals a novel genotype and evidence of natural recombination in coronavirus HKU1.
Patrick C. Y. Woo,Susanna K. P. Lau,Cyril C. Y. Yip,Yi Huang,Hoi Wah Tsoi,Kwok-Hung Chan,Kwok-Yung Yuen +6 more
TL;DR: The present study represents the first evidence for natural recombination in coronavirus associated with human infection.